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| Mesostructured Fibrils Exfoliated in Deep Eutectic Solvent as Building Blocks of Collagen Membranes | |
| 2023-10 | |
| Source Publication | POLYMERS
 |
| EISSN | 2073-4360 |
| Volume | 15Issue:19 |
| Status | 已发表 |
| DOI | 10.3390/polym15194008 |
| Abstract | The mesoscale components of collagen (nanofibrils, fibrils, and fiber bundles) are well organized in native tissues, resulting in superior properties and diverse functions. In this paper, we present a simple and controlled liquid exfoliation method to directly extract medium-sized collagen fibers ranging from 102 to 159 nm in diameter from bovine Achilles tendon using urea/hydrochloric acid and a deep eutectic solvent (DES). In situ observations under polarized light microscopy (POM) and molecular dynamics simulations revealed the effects of urea and GuHCl on tendon collagen. FTIR study results confirmed that these fibrils retained the typical structural characteristics of type I collagen. These shed collagen fibrils were then used as building blocks to create independent collagen membranes with good and stable mechanical properties, excellent barrier properties, and cell compatibility. A new method for collagen processing is provided in this work by using DES-assisted liquid exfoliation for constructing robust collagen membranes with mesoscale collagen fibrils as building blocks. © 2023 by the authors. |
| Keyword | Biomechanics Collagen Eutectics Mammals Metabolism Molecular dynamics Solvents Tendons Achilles tendons Bovine achilles tendon Building blockes Collagen fibrils Collagen membrane Deep eutectic solvents Exfoliation Fibril Liquid exfoliations Mesostructured |
| URL | 查看原文 |
| Indexed By | EI ; SCI |
| Language | 英语 |
| WOS Research Area | Polymer Science |
| WOS Subject | Polymer Science |
| WOS ID | WOS:001081556000001 |
| Publisher | Multidisciplinary Digital Publishing Institute (MDPI) |
| EI Accession Number | 20234214906695 |
| EI Keywords | Urea |
| EI Classification Number | 461.2 Biological Materials and Tissue Engineering ; 461.3 Biomechanics, Bionics and Biomimetics ; 531.2 Metallography ; 801.4 Physical Chemistry ; 803 Chemical Agents and Basic Industrial Chemicals ; 804.1 Organic Compounds |
| Original Document Type | Journal article (JA) |
| Document Type | 期刊论文 |
| Identifier | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/340973 |
| Collection | 物质科学与技术学院 物质科学与技术学院_外聘教师 物质科学与技术学院_PI研究组_凌盛杰组 |
| Corresponding Author | Pei, Ying; Ling, Shengjie; Tian, Huafeng |
| Affiliation | 1.Shaanxi Univ Sci & Technol, Minist Educ, Key Lab Auxiliary Chem & Technol Chem Ind, Xian 710021, Peoples R China 2.Beijing Technol & Business Univ, China Natl Light Ind Council, Key Lab Proc & Qual Evaluat Technol Green Plast, Beijing 100048, Peoples R China 3.Zhengzhou Univ, Coll Mat Sci & Engn, Zhengzhou 450001, Peoples R China 4.Shanghai Tech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China |
| Corresponding Author Affilication | School of Physical Science and Technology |
| Recommended Citation GB/T 7714 | Pei, Ying,Li, Wei,Wang, Lu,et al. Mesostructured Fibrils Exfoliated in Deep Eutectic Solvent as Building Blocks of Collagen Membranes[J]. POLYMERS,2023,15(19). |
| APA | Pei, Ying.,Li, Wei.,Wang, Lu.,Cui, Jing.,Li, Lu.,...&Tian, Huafeng.(2023).Mesostructured Fibrils Exfoliated in Deep Eutectic Solvent as Building Blocks of Collagen Membranes.POLYMERS,15(19). |
| MLA | Pei, Ying,et al."Mesostructured Fibrils Exfoliated in Deep Eutectic Solvent as Building Blocks of Collagen Membranes".POLYMERS 15.19(2023). |
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