ShanghaiTech University Knowledge Management System
| Solvent-Free Mechanoradical-Mediated Minisci-Type C-H Alkylation of N-Heteroarenes | |
| 2023-10-01 | |
| 发表期刊 | ORGANIC LETTERS (IF:4.9[JCR-2023],4.5[5-Year]) |
| ISSN | 1523-7060 |
| EISSN | 1523-7052 |
| 发表状态 | 已发表 |
| DOI | 10.1021/acs.orglett.3c02480 |
| 摘要 | An environmentally friendly new C-H alkylation method of N-heteroarenes facilitated by mechanochemistry is described. Under solvent-free ball-milling, mechanoradicals (SO4 center dot -) were generated from persulfate via in situ homolysis in the solid state, at as low as -50 C-degrees. These highly oxidizing radicals readily transform alkyl trifluoroborate salts to their corresponding carbon-based radicals for subsequent C-C bond formation with N-heterocycles. Mechanistic studies unambiguously confirmed the involvement of both oxygen- and alkyl-radical-based intermediates. |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | ShanghaiTech University[SPST-AIC10112914] |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| WOS记录号 | WOS:001077674800001 |
| 出版者 | AMER CHEMICAL SOC |
| 引用统计 | 正在获取...
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| 文献类型 | 期刊论文 |
| 条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/340930 |
| 专题 | 物质科学与技术学院 物质科学与技术学院_博士生 物质科学与技术学院_PI研究组_甄家劲组 |
| 通讯作者 | Yan, KaKing |
| 作者单位 | ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China |
| 第一作者单位 | 物质科学与技术学院 |
| 通讯作者单位 | 物质科学与技术学院 |
| 第一作者的第一单位 | 物质科学与技术学院 |
| 推荐引用方式 GB/T 7714 | Gu, Xiang,Wang, Taoyong,Yan, KaKing. Solvent-Free Mechanoradical-Mediated Minisci-Type C-H Alkylation of N-Heteroarenes[J]. ORGANIC LETTERS,2023. |
| APA | Gu, Xiang,Wang, Taoyong,&Yan, KaKing.(2023).Solvent-Free Mechanoradical-Mediated Minisci-Type C-H Alkylation of N-Heteroarenes.ORGANIC LETTERS. |
| MLA | Gu, Xiang,et al."Solvent-Free Mechanoradical-Mediated Minisci-Type C-H Alkylation of N-Heteroarenes".ORGANIC LETTERS (2023). |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
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