Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation

doi:10.1105/tpc.16.00579

	Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation
	Wang, Jin 1,2,3; Tian, Caihuan 1,2; Zhang, Cui 1,2; Shi, Bihai 1,2,3; Cao, Xiuwei 1,2,3; Zhang, Tian-Qi 4,5; Zhao, Zhong 6; Wang, Jia-Wei4,7 ; Jiao, Yuling 1,2,3
	2017-06
发表期刊	PLANT CELL
ISSN	1040-4651
卷号	29 期号:6 页码:1373-1387
发表状态	已发表
DOI	10.1105/tpc.16.00579
摘要	The homeodomain transcription factor WUSCHEL (WUS) defines the shoot stem cell niche, but the mechanisms underlying the establishment of WUS expression remain unclear. Here, we show that cytokinin signaling precedes WUS expression in leaf axils and activates WUS expression de novo in the leaf axil to promote axillary meristem initiation. Furthermore, type-B Arabidopsis response regulator proteins, which are transcriptional activators in the cytokinin signaling pathway, directly bind to the WUS promoter and activate its expression. Finally, we show that cytokinin activation of WUS in the leaf axil correlates with increased histone acetylation and methylation markers associated with transcriptional activation, supporting the fact that WUS expression requires a permissive epigenetic environment to restrict it to highly defined meristematic tissues. Taken together, these findings explain how cytokinin regulates axillary meristem initiation and establish a mechanistic framework for the postembryonic establishment of the shoot stem cell niche.
收录类别	SCI
语种	英语
资助项目	National Basic Research Program of China (973 Program)[2014CB943500]
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
WOS类目	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
WOS记录号	WOS:000404989600017
出版者	AMER SOC PLANT BIOLOGISTS
WOS关键词	ARABIDOPSIS SHOOT MERISTEM ; STEM-CELL MAINTENANCE ; B RESPONSE REGULATORS ; FLORAL MERISTEMS ; AUXIN DEPLETION ; APICAL MERISTEM ; ROOT-GROWTH ; GENE ; THALIANA ; LEAVES
原始文献类型	Article
通讯作者	Jiao, Yuling
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/2920
专题	生命科学与技术学院_特聘教授组_王佳伟组
通讯作者	Jiao, Yuling
作者单位	1.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing 100101, Peoples R China 2.Natl Ctr Plant Gene Res, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Shanghai Inst Biol Sci, Inst Plant Physiol & Ecol, CAS Ctr Excellence Mol Plant Sci, Natl Key Lab Plant Mol Genet, Shanghai 200032, Peoples R China 5.Univ Chinese Acad Sci, Shanghai 200032, Peoples R China 6.Univ Sci & Technol China, Sch Life Sci, Hefei 230027, Anhui, Peoples R China 7.ShanghaiTech Univ, Shanghai 200031, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jin,Tian, Caihuan,Zhang, Cui,et al. Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation[J]. PLANT CELL,2017,29(6):1373-1387.
APA	Wang, Jin.,Tian, Caihuan.,Zhang, Cui.,Shi, Bihai.,Cao, Xiuwei.,...&Jiao, Yuling.(2017).Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation.PLANT CELL,29(6),1373-1387.
MLA	Wang, Jin,et al."Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation".PLANT CELL 29.6(2017):1373-1387.