Dual-contrast nonlinear photoacoustic sensing based on quasi-CW single-pulsed laser

doi:10.1117/12.2502070

	Dual-contrast nonlinear photoacoustic sensing based on quasi-CW single-pulsed laser
	Lan, Hengrong1 ; Duan, Tinyang1 ; Jiang, Daohuai1 ; Zhong, Hongtao1 ; Zhou, Meng1,2 ; Gao, Fei1
	2018
会议录名称	OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS VIII
卷号	10820
发表状态	已发表
DOI	10.1117/12.2502070
摘要	Photoacoustic tomography (PAT) is a non-invasive imaging technique which provided high lateral resolution and axial resolution. Conventional linear photoacoustic (PA) imaging has been widely applied to state-of-art PA system, which excited by short pulse laser. Recently, nonlinear photoacoustic effect has been excavated and utilized, which indicates the different character with linear PA by dual-pulse laser. In this paper, we report a dual-contrast photoacoustic sensing by quasi-CW nonlinear PA effect. Using the high-repetition pulsed laser, and two different contrast imaging were extracted. Unless conventional contrast that using short laser pulse by detected tissue light absorption, we extracted another contrast that indicated the rising of temperature. The quasi-CW nonlinear PA effect could be illustrated by a simple mathematical derivation. The dual-contrast PA imaging have been demonstrated by experiment in vitro and ex vivo imaging. The results indicate different heat absorbency of different materials, which could be utilized to distinguish materials and intensify imaging contrast. Compared with conventional PA imaging, the proposed method has more scope of works and potential applications.
关键词	Photoacoustic imaging nonlinear PA contrast quasi-CW
出版地	1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
会议地点	Beijing, China
收录类别	CPCI ; CPCI-S ; EI
语种	英语
资助项目	Natural Science Foundation of China[61805139]
WOS研究方向	Optics
WOS类目	Optics
WOS记录号	WOS:000451757000057
出版者	SPIE-INT SOC OPTICAL ENGINEERING
EI入藏号	20184806157228
EI主题词	Excited states ; Health care ; Laser pulses ; Light absorption ; Public address systems ; Pulsed lasers
EI分类号	Health Care:461.7 ; Light/Optics:741.1 ; Lasers, General:744.1 ; Sound Devices, Equipment and Systems:752 ; Atomic and Molecular Physics:931.3
WOS关键词	OXYGEN-SATURATION ; TOMOGRAPHY ; MICROSCOPY ; AGENT
原始文献类型	Proceedings Paper
引用统计	正在获取...
文献类型	会议论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/29034
专题	信息科学与技术学院_硕士生信息科学与技术学院_PI研究组_高飞组信息科学与技术学院_博士生
通讯作者	Gao, Fei
作者单位	1.ShanghaiTech Univ, Sch Informat Sci & Technol, Hybrid Imaging Syst Lab, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai 201210, Peoples R China
第一作者单位	信息科学与技术学院
通讯作者单位	信息科学与技术学院
第一作者的第一单位	信息科学与技术学院
推荐引用方式 GB/T 7714	Lan, Hengrong,Duan, Tinyang,Jiang, Daohuai,et al. Dual-contrast nonlinear photoacoustic sensing based on quasi-CW single-pulsed laser[C]. 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA:SPIE-INT SOC OPTICAL ENGINEERING,2018.