ShanghaiTech University Knowledge Management System
Cell-free protein synthesis: Recent advances in bacterial extract sources and expanded applications | |
2019-01-15 | |
发表期刊 | BIOCHEMICAL ENGINEERING JOURNAL (IF:3.7[JCR-2023],3.5[5-Year]) |
ISSN | 1369-703X |
卷号 | 141页码:182-189 |
发表状态 | 已发表 |
DOI | 10.1016/j.bej.2018.10.023 |
摘要 | Cell-free protein synthesis (CFPS) is a technology for the production of proteins in vitro, which has emerged as a robust platform for biotechnology and synthetic biology applications. Recently, the renewed scientific interest in CFPS technology has driven the rapid development of cell-free biotechnology. In this review, we focus on the very recent advances and applications of CFPS with a time frame from 2016 to the middle of 2018. First, we introduce newly developed CFPS systems from different microorganisms including Streptomyces species, Bacillus subtilis, Pseudomonas putida, and Vibrio natriegens. Then, we summarize emerging applications of CFPS for next-generation biomanufacturing. With that, we discuss the future perspectives of CFPS and its potential for cost-effective, high-yielding production of therapeutics, chemicals, and materials. |
关键词 | Cell-free protein synthesis In vitro transcription-translation Synthetic biology Protein expression |
收录类别 | EI ; SCIE ; SCI |
语种 | 英语 |
资助项目 | Shanghai Pujiang Program[18PJ1408000] |
WOS研究方向 | Biotechnology & Applied Microbiology ; Engineering |
WOS类目 | Biotechnology & Applied Microbiology ; Engineering, Chemical |
WOS记录号 | WOS:000453623900019 |
出版者 | ELSEVIER SCIENCE BV |
EI入藏号 | 20184406024562 |
EI主题词 | Bacteria ; Bacteriology ; Biotechnology ; Cells ; Cost effectiveness ; Cytology ; Proteins |
EI分类号 | Biological Materials and Tissue Engineering:461.2 ; Biotechnology:461.8 ; Organic Compounds:804.1 ; Industrial Economics:911.2 |
WOS关键词 | ESCHERICHIA-COLI ; FREE EXPRESSION ; MEMBRANE-PROTEINS ; SYNTHESIS SYSTEMS ; FREE PLATFORM ; AMINO-ACIDS ; BIOLOGY ; TRANSLATION ; TRANSCRIPTION ; BIOSYNTHESIS |
原始文献类型 | Article |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/28736 |
专题 | 物质科学与技术学院_PI研究组_李健组 物质科学与技术学院_硕士生 生命科学与技术学院_本科生 |
通讯作者 | Li, Jian |
作者单位 | 1.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China |
第一作者单位 | 物质科学与技术学院 |
通讯作者单位 | 物质科学与技术学院 |
第一作者的第一单位 | 物质科学与技术学院 |
推荐引用方式 GB/T 7714 | Liu, Wan-Qiu,Zhang, Lingkai,Chen, Mingzhe,et al. Cell-free protein synthesis: Recent advances in bacterial extract sources and expanded applications[J]. BIOCHEMICAL ENGINEERING JOURNAL,2019,141:182-189. |
APA | Liu, Wan-Qiu,Zhang, Lingkai,Chen, Mingzhe,&Li, Jian.(2019).Cell-free protein synthesis: Recent advances in bacterial extract sources and expanded applications.BIOCHEMICAL ENGINEERING JOURNAL,141,182-189. |
MLA | Liu, Wan-Qiu,et al."Cell-free protein synthesis: Recent advances in bacterial extract sources and expanded applications".BIOCHEMICAL ENGINEERING JOURNAL 141(2019):182-189. |
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