Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring

doi:10.3390/mi13101560

	Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring
	Fei, Sitao; Ren, Hao
	2022-10
发表期刊	MICROMACHINES (IF:3.0[JCR-2023],3.0[5-Year])
EISSN	2072-666X
卷号	13 期号:10
DOI	10.3390/mi13101560
摘要	Nowadays, the development of real-time water quality monitoring sensors is critical. However, traditional water monitoring technologies, such as enzyme-linked immunosorbent assay (ELISA), liquid chromatography, mass spectroscopy, luminescence screening, surface plasma resonance (SPR), and analysis of living bioindicators, are either time consuming or require expensive equipment and special laboratories. Because of the low cost, self-sustainability, direct current output and real-time response, microbial fuel cells (MFCs) have been implemented as biosensors for water toxicity monitoring. In this paper, we report a microscale MFC biosensor to study the dose-response curve of exoelectrogen to toxic compounds in water. The microscale MFC biosensor has an anode chamber volume of 200 mu L, which requires less sample consumption for water toxicity monitoring compared with macroscale or mesoscale MFC biosensors. For the first time, the MFC biosensor is exposed to a large formaldehyde concentration range of more than 3 orders of magnitudes, from a low concentration of 1 x 10(-6) g/L to a high concentration of 3 x 10(-3) g/L in water, while prior studies investigated limited formaldehyde concentration ranges, such as a small concentration range of 1 x 10(-4) g/L to 2 x 10(-3) g/L or only one high concentration of 0.1 g/L. As a result, for the first time, a sigmoid dose-response relationship of normalized dose-response versus formaldehyde concentration in water is observed, in agreement with traditional toxicology dose-response curve obtained by other measurement techniques. The biosensor has potential applications in determining dose-response curves for toxic compounds and detecting toxic compounds in water.
关键词	microbial fuel cell (MFC) biosensor dose-response curve water toxicity monitoring exoelectrogen
URL	查看原文
收录类别	SCIE ; EI
语种	英语
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation ; Physics
WOS类目	Chemistry, Analytical ; Nanoscience & Nanotechnology ; Instruments & Instrumentation ; Physics, Applied
WOS记录号	WOS:000873217400001
出版者	MDPI
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/243324
专题	信息科学与技术学院_硕士生信息科学与技术学院_PI研究组_任豪组
通讯作者	Ren, Hao
作者单位	ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai 201210, Peoples R China
第一作者单位	信息科学与技术学院
通讯作者单位	信息科学与技术学院
第一作者的第一单位	信息科学与技术学院
推荐引用方式 GB/T 7714	Fei, Sitao,Ren, Hao. Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring[J]. MICROMACHINES,2022,13(10).
APA	Fei, Sitao,&Ren, Hao.(2022).Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring.MICROMACHINES,13(10).
MLA	Fei, Sitao,et al."Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring".MICROMACHINES 13.10(2022).