Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407

doi:10.1007/s00438-017-1403-4

	Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407
	Huang, Yun-Zhi 1; Wei, Lan-Hai 1,2; Yan, Shi 1; Wen, Shao-Qing 1; Wang, Chuan-Chao 3; Yang, Ya-Jun 1; Wang, Ling-Xiang 1; Lu, Yan 4; Zhang, Chao 4,5; Xu, Shu-Hua1,4,5,6 ; Yao, Da-Li 7; Jin, Li 1; Li, Hui 1
	2018-06
发表期刊	MOLECULAR GENETICS AND GENOMICS (IF:2.3[JCR-2023],2.5[5-Year])
ISSN	1617-4615
卷号	293 期号:3 页码:657-663
发表状态	已发表
DOI	10.1007/s00438-017-1403-4
摘要	The Y-chromosome haplogroup C2c1a1a1-M407 is a predominant paternal lineage in Mongolic-speaking populations, especially in Buryats and Kalmyks. However, the origin and internal phylogeny of C2c1a1a1-M407 have not been investigated in detail. In this study, we analyzed twenty-three Y-chromosome sequences of haplogroup C2c1a1a1-M407 and its most closely related clades. We generated a high-resolution phylogenetic tree of haplogroup C2c1a1a1-M407 and its upstream clade C2c1a1-CTS2657, including 32 subclades and 144 non-private Y-chromosome polymorphisms. We discover that all available C2c1a1a1-M407 samples from Mongolic-speaking populations belong to its newly defined downstream clade C2c1a1a1b-F8465, whereas all samples of C2c1a1-CTS2657(xF8465) come from northern Han Chinese, Korean, and Japanese. Furthermore, we observe that C2c1a1a1b-F8465 and its subclade C2c1a1a1b1-F8536 expanded at approximately 0.86 and 0.44 thousand years ago, respectively. Therefore, we conclude that C2c1a1a1-M407 in Mongolic-speaking populations has originated from northeastern Asia. C2c1a1a1b1-F8536, the newly defined subclade of C2c1a1a1-M407, probably represents the genetic relationships between ancient Oyrats, modern Kalmyks, Mongolians, and Buryats.
关键词	C2c1a1a1-M407 Mongolic-speaking Han Chinese Y-chromosome sequence
收录类别	SCI ; SCIE
语种	英语
资助项目	Science and Technology Commission of Shanghai Municipality (STCSM)[14YF1406800]
WOS研究方向	Biochemistry & Molecular Biology ; Genetics & Heredity
WOS类目	Biochemistry & Molecular Biology ; Genetics & Heredity
WOS记录号	WOS:000431943500008
出版者	SPRINGER HEIDELBERG
WOS关键词	BURROWS-WHEELER TRANSFORM ; GENOME SEQUENCE ; DIVERGENCE TIME ; READ ALIGNMENT ; DIVERSITY ; POPULATIONS ; KALMYKS ; STR
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/20823
专题	生命科学与技术学院_特聘教授组_徐书华组
通讯作者	Li, Hui
作者单位	1.Fudan Univ, Sch Life Sci, Collaborat Innovat Ctr Genet & Dev, MOE Key Lab Contemporary Anthropol, Shanghai 200438, Peoples R China 2.Inst Natl Langues & Civilisat Orientales, F-75013 Paris, France 3.Xiamen Univ, Dept Anthropol & Ethnol, Xiamen 361005, Peoples R China 4.Chinese Acad Sci, Chinese Acad Sci & Max Planck Soc CAS MPG Partner, Shanghai Inst Biol Sci, Shanghai 200031, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 7.Fudan Univ, Ctr Hist Geog Studies, Shanghai 200433, Peoples R China
推荐引用方式 GB/T 7714	Huang, Yun-Zhi,Wei, Lan-Hai,Yan, Shi,et al. Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407[J]. MOLECULAR GENETICS AND GENOMICS,2018,293(3):657-663.
APA	Huang, Yun-Zhi.,Wei, Lan-Hai.,Yan, Shi.,Wen, Shao-Qing.,Wang, Chuan-Chao.,...&Li, Hui.(2018).Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407.MOLECULAR GENETICS AND GENOMICS,293(3),657-663.
MLA	Huang, Yun-Zhi,et al."Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407".MOLECULAR GENETICS AND GENOMICS 293.3(2018):657-663.