Three-dimensionally printed navigational template: a promising guiding approach for lung biopsy

doi:10.21037/tlcr-22-172

	Three-dimensionally printed navigational template: a promising guiding approach for lung biopsy
	Haoran, E.1; Chen, Jiafei 1; Sun, Weiyan 1; Zhang, Yikai2 ; Ren, Shengxiang 3; Shi, Jingyun 4; Wen, Yaofeng 5; Su, Chunxia 3; Ni, Jian 3; Zhang, Lei 1; He, Yayi 3; Chen, Bin 3; Casal, Roberto F.6; Kheir, Fayez 7; Ishiwata, Tsukasa 8; Zhang, Jie 3; Zhao, Deping 1; Chen, Chang 1,9,10,11
	2022-03-01
发表期刊	TRANSLATIONAL LUNG CANCER RESEARCH (IF:4.0[JCR-2023],4.3[5-Year])
ISSN	2218-6751
EISSN	2226-4477
发表状态	已发表
DOI	10.21037/tlcr-22-172
摘要	["Background: Percutaneous transthoracic lung biopsy is customarily conducted under computed tomography (CT) guidance, which primarily depends on the conductors' experience and inevitably contributes to long procedural duration and radiation exposure. Novel technique facilitating lung biopsy is currently demanded.","Methods: Based on the reconstructed anatomical information of CT scans, a three-dimensionally printed navigational template was customized to guide fine-needle aspiration (FNA). The needle insertion site and angle could be indicated by the template after proper placement according to the reference landmarks. From June 2020 to August 2020, patients with peripheral indeterminate lung lesions30 mm in diameter were enrolled in a pilot trial. Cases were considered successful when the virtual line indicated by the template in the first CT scan was pointing at the target, and the rate of success was recorded. The insertion deviation, procedural duration, radiation exposure, biopsy-related complications, and diagnostic yield were documented as well.","Results: A total of 20 patients consented to participate, and 2 withdrew. The remaining 18 participants consisting of 11 men and 7 women with a median age of 63 [inter-quartile range (TOR), 50-68] years and a median body mass index (BMI) of 23.5 (IQR, 20.8-25.8) kg/m(2) received template-guided FNA. The median nodule size of the patients was 41.2 (IQR, 36.2-51.9) mm and 17 lesions were successfully targeted (success rate, 94.4%). One lesion was not reached through the designed trajectory due to an unpredictable alteration of the lesion's location resulting from pleural effusion. The median deviation between the actual position of the needle tip and the designed route was 9.4 (IQR, 6.8-11.7) mm. The median procedural duration was 10.7 (IQR, 9.7-11.8) min, and the median radiation exposure was 220.9 (IQR, 198.6-249.5) mGyxcm. No major biopsy-related complication was encountered. Definitive diagnosis of malignancy was reached in 13 of the 17 (76.5%) participants.","Conclusions: The feasibility and safety of navigational template-guided FNA were preliminarily validated in lung biopsy cohort. Nonetheless, patients with pleural effusion were not recommended to undergo FNA guided by such technique."]
关键词	Lung biopsy three-dimensional printing (3D printing) computed tomography (CT) fine-needle aspiration (FNA)
URL	查看原文
收录类别	SCI ; SCIE
语种	英语
资助项目	National Natural Science Foundation of China[NSFC81770091] ; Clinical Research Plan of Shanghai Hospital Development Center[SHDC2020CR1021B] ; Science and Technology Commission of Shanghai Municipality["21S31905200","20YF1440900"] ; Clinical Research Foundation of Shanghai Pulmonary Hospital[FKLY20007] ; Shanghai Pulmonary Hospital[SKPY2021005]
WOS研究方向	Oncology ; Respiratory System
WOS类目	Oncology ; Respiratory System
WOS记录号	WOS:000775672500001
出版者	AME PUBL CO
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/171468
专题	信息科学与技术学院_本科生
通讯作者	Zhang, Jie; Zhao, Deping; Chen, Chang
作者单位	1.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Thorac Surg, 507 Zhengmin Rd, Shanghai 200443, Peoples R China 2.ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai, Peoples R China 3.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Med Oncol, 507 Zhengmin Rd, Shanghai 200443, Peoples R China 4.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Radiol, Shanghai, Peoples R China 5.Lanhui Med Technol Co Ltd, Shanghai, Peoples R China 6.Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Houston, TX 77030 USA 7.Harvard Med Sch, Massachusetts Gen Hosp, Dept Med, Div Pulm & Crit Care Med, Boston, MA 02115 USA 8.Univ Hlth Network, Toronto Gen Hosp, Div Thorac Surg, Toronto, ON, Canada 9.Int Sci & Technol Cooperat Base Dev & Applicat Ke, Lanzhou, Peoples R China 10.First Hosp Lanzhou Univ, Dept Thorac Surg, Lanzhou, Peoples R China 11.First Peoples Hosp Linhai, Prov Famous Expert Workstn, Taizhou, Peoples R China
推荐引用方式 GB/T 7714	Haoran, E.,Chen, Jiafei,Sun, Weiyan,et al. Three-dimensionally printed navigational template: a promising guiding approach for lung biopsy[J]. TRANSLATIONAL LUNG CANCER RESEARCH,2022.
APA	Haoran, E..,Chen, Jiafei.,Sun, Weiyan.,Zhang, Yikai.,Ren, Shengxiang.,...&Chen, Chang.(2022).Three-dimensionally printed navigational template: a promising guiding approach for lung biopsy.TRANSLATIONAL LUNG CANCER RESEARCH.
MLA	Haoran, E.,et al."Three-dimensionally printed navigational template: a promising guiding approach for lung biopsy".TRANSLATIONAL LUNG CANCER RESEARCH (2022).