Construction of a magnetic covalent organic framework for magnetic solid-phase extraction of AFM1 and AFM2 in milk prior to quantification by LC-MS/MS

doi:10.1007/s00604-021-05090-8

	Construction of a magnetic covalent organic framework for magnetic solid-phase extraction of AFM1 and AFM2 in milk prior to quantification by LC-MS/MS
	Li, Jie 1,2; Xu, Xiuli 1; Wang, Xiujuan 1; Li, Chen3 ; Feng, Xuesong 2; Zhang, Yuan 2; Zhang, Feng 1
	2022-04
发表期刊	MICROCHIMICA ACTA (IF:5.3[JCR-2023],5.0[5-Year])
ISSN	0026-3672
EISSN	1436-5073
卷号	189 期号:4
发表状态	已发表
DOI	10.1007/s00604-021-05090-8
摘要	["A magnetic covalent organic framework (M-COF) was designed and selected as sorbent for magnetic solid-phase extraction (MSPE) of AFM1 and AFM2 in milk, followed by LC-MS/MS analysis. The application of 2,5-Dihydroxy-1,4-benzenedicarboxaldehyde (Dt) and 4',5'-bis(4-aminopheny1)-[1,1':2',1 ''-terphenyl]-4,4 ''-diamine (BAPTPDA) as monomers endows M-COF excellent properties for adsorbing AFM1 and AFM2. The morphology, structure, stability, and magnetism of the Fe3O4@COF(BAPTPDA-Dt) were characterized by various techniques including scanning electron microscopy, transmission electron microscopy, FTIR, thermogravimetric analysis, and vibrating sample magnetometer. The Fe3O4 microspheres were covered by COF shells. Fe3O4@COF exhibited excellent magnetism and stability. Some parameters that may influence the adsorption efficiency of MSPE were also optimized, making the extraction process more effective, time-saving (about 3 min), and less organic-reagent-consuming (only 4 mL of acetonitrile required). It is noteworthy that the Fe3O4@ COF(BAPTPDA-Dt) can be reutilized more than 8 times. The AFM1 and AFM2 were determined by LC-MS/MS. The LODs for AFM1 and AFM2 were in the range 0.0069 to 0.0078 mu g kg(-1). A wide linearity range (0.01-100 mu g kg(-1)) with coefficients of determination (R-2) ranging from 0.9998 to 0.9999 was obtained. The recoveries at four spiked concentrations (0.05, 0.5, 5, and 50 mu g kg(-1)) in the milk matrix ranged from 85.2 to 106.5%. The intraday RSDs and the interday RSDs were in the range 1.74-4.58% and 2.65-6.69%, respectively. The matrix effect (9.3% for AFM1 and 6.7% for AFM2) was also significantly lower than that observed in other work . Overall, the established method has provided a powerful tool for rapid pretreatment and sensitive determination of AFM1 and AFM2 in milk with negligible matrix effect, presenting important value in toxicant determination.","[GRAPHICS]","."]
关键词	Magnetic solid-phase extraction Fe3O4@COF(BAPTPDA-Dt) LC-MS/MS AFM1 and AFM2 Milk analysis
URL	查看原文
收录类别	SCI ; SCIE
语种	英语
资助项目	National Key Research and Development Program of China[2017YFC1601600]
WOS研究方向	Chemistry
WOS类目	Chemistry, Analytical
WOS记录号	WOS:000770627300002
出版者	SPRINGER WIEN
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/169224
专题	生命科学与技术学院_硕士生
通讯作者	Zhang, Feng
作者单位	1.Chinese Acad Inspect & Quarantine, Inst Food Safety, Beijing 100176, Peoples R China 2.China Med Univ, Sch Pharm, Shenyang 110122, Liaoning, Peoples R China 3.ShanghaiTech Univ, Life Sci & Technol, Shanghai 201210, Peoples R China
推荐引用方式 GB/T 7714	Li, Jie,Xu, Xiuli,Wang, Xiujuan,et al. Construction of a magnetic covalent organic framework for magnetic solid-phase extraction of AFM1 and AFM2 in milk prior to quantification by LC-MS/MS[J]. MICROCHIMICA ACTA,2022,189(4).
APA	Li, Jie.,Xu, Xiuli.,Wang, Xiujuan.,Li, Chen.,Feng, Xuesong.,...&Zhang, Feng.(2022).Construction of a magnetic covalent organic framework for magnetic solid-phase extraction of AFM1 and AFM2 in milk prior to quantification by LC-MS/MS.MICROCHIMICA ACTA,189(4).
MLA	Li, Jie,et al."Construction of a magnetic covalent organic framework for magnetic solid-phase extraction of AFM1 and AFM2 in milk prior to quantification by LC-MS/MS".MICROCHIMICA ACTA 189.4(2022).