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| A robust mechanism for resetting juvenility during each generation in Arabidopsis | |
| 2022-03 | |
| 发表期刊 | NATURE PLANTS (IF:15.8[JCR-2023],17.1[5-Year]) |
| ISSN | 2055-026X |
| EISSN | 2055-0278 |
| 卷号 | 8期号:3 |
| 发表状态 | 已发表 |
| DOI | 10.1038/s41477-022-01110-4 |
| 摘要 | ["In Arabidopsis, microRNAs control the transition from juvenile to adult states. The study, using genomic, genetic and molecular approaches, investigates how miR156 and miR157 are re-activated at each generation.","Multicellular organisms undergo several developmental transitions during their life cycles. In contrast to animals, the plant germline is derived from adult somatic cells. As such, the juvenility of a plant must be reset in each generation. Previous studies have demonstrated that the decline in the levels of miR156/7 with age drives plant maturation. Here we show that the resetting of plant juvenility during each generation is mediated by de novo activation of MIR156/7 in Arabidopsis. Blocking this process leads to a shortened juvenile phase and premature flowering in the offspring. In particular, an Arabidopsis plant devoid of miR156/7 flowers even without formation of rosette leaves in long days. Mechanistically, we find that different MIR156/7 genes are reset at different developmental stages through distinct reprogramming routes. Among these genes, MIR156A, B and C are activated de novo during sexual reproduction and embryogenesis, while MIR157A and C are reset upon seed germination. This redundancy generates a robust reset mechanism that ensures accurate restoration of the juvenile phase in each plant generation."] |
| URL | 查看原文 |
| 收录类别 | SCI ; SCIE |
| 语种 | 英语 |
| 资助项目 | National Key Research and Development Program[2016YFA0500800] ; National Natural Science Foundation of China[31788103,31721001] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB27030101] ; Science and Technology Commission of Shanghai Municipality[18JC1415000] ; Shanghai Post-doctoral Excellence Program[2019029] |
| WOS研究方向 | Plant Sciences |
| WOS类目 | Plant Sciences |
| WOS记录号 | WOS:000772102900015 |
| 出版者 | NATURE PORTFOLIO |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/169213 |
| 专题 | 生命科学与技术学院_博士生 生命科学与技术学院_特聘教授组_王佳伟组 |
| 通讯作者 | Wang, Jia-Wei |
| 作者单位 | 1.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci CEMPS, Inst Plant Physiol & Ecol SIPPE, Natl Key Lab Plant Mol Genet, Shanghai, Peoples R China 2.Univ Chinese Acad Sci, Shanghai, Peoples R China 3.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China 4.CAS Ctr Excellence Mol Plant Sci, Shanghai Ctr Plant Stress Biol, Shanghai, Peoples R China |
| 通讯作者单位 | 生命科学与技术学院 |
| 推荐引用方式 GB/T 7714 | Gao, Jian,Zhang, Ke,Cheng, Ying-Juan,et al. A robust mechanism for resetting juvenility during each generation in Arabidopsis[J]. NATURE PLANTS,2022,8(3). |
| APA | Gao, Jian.,Zhang, Ke.,Cheng, Ying-Juan.,Yu, Sha.,Shang, Guan-Dong.,...&Wang, Jia-Wei.(2022).A robust mechanism for resetting juvenility during each generation in Arabidopsis.NATURE PLANTS,8(3). |
| MLA | Gao, Jian,et al."A robust mechanism for resetting juvenility during each generation in Arabidopsis".NATURE PLANTS 8.3(2022). |
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