TGF-beta signaling pathway in early mouse development and embryonic stem cells

doi:10.1093/abbs/gmx120

	TGF-beta signaling pathway in early mouse development and embryonic stem cells
	Liu, Chang 1; Peng, Guangdun 1; Jing, Naihe1,2
	2018-01
发表期刊	ACTA BIOCHIMICA ET BIOPHYSICA SINICA
ISSN	1672-9145
卷号	50 期号:1 页码:68-73
发表状态	已发表
DOI	10.1093/abbs/gmx120
摘要	TGF-beta superfamily signaling pathways essentially contribute to the broad spectrum of early developmental events including embryonic patterning, cell fate determination and dynamic movements. In this review, we first introduced some key developmental processes that require TGF-beta signaling to show the fundamental importance of these pathways. Then we discuss how their activities are regulated, and new findings about how the TGF-beta superfamily ligands bind to the chromatin to regulate transcription during embryo development.
关键词	TGF-beta mouse embryo embryonic stem cells Smad transcription factor chromatin modification
收录类别	SCI ; SCIE ; CSCD
语种	英语
资助项目	National Natural Science Foundation of China[31430058] ; National Natural Science Foundation of China[31571513] ; National Natural Science Foundation of China[31630043] ; National Natural Science Foundation of China[91519314] ; National Natural Science Foundation of China[31661143042]
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics
WOS类目	Biochemistry & Molecular Biology ; Biophysics
WOS记录号	WOS:000423304200007
CSCD记录号	CSCD:6273041
出版者	OXFORD UNIV PRESS
WOS关键词	ANTERIOR-POSTERIOR POLARITY ; VISCERAL ENDODERM ; PRIMITIVE STREAK ; FATE DECISIONS ; NEURAL DIFFERENTIATION ; SYNEXPRESSION GROUP ; AXIS FORMATION ; SELF-RENEWAL ; NODE ; EPIBLAST
原始文献类型	Review
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/16274
专题	生命科学与技术学院_特聘教授组_景乃禾组
通讯作者	Jing, Naihe
作者单位	1.Univ Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, Chinese Acad Sci, CAS Ctr Excellence Mol Cell Sci,State Key Lab Cel, Shanghai 200031, Peoples R China 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Liu, Chang,Peng, Guangdun,Jing, Naihe. TGF-beta signaling pathway in early mouse development and embryonic stem cells[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2018,50(1):68-73.
APA	Liu, Chang,Peng, Guangdun,&Jing, Naihe.(2018).TGF-beta signaling pathway in early mouse development and embryonic stem cells.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,50(1),68-73.
MLA	Liu, Chang,et al."TGF-beta signaling pathway in early mouse development and embryonic stem cells".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 50.1(2018):68-73.