Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis

doi:10.1364/BOE.8.005825

	Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis
	Yao, Shengkun1 ; Zong, Yunbing 2,3; Huang, Xu 4; Liu, Yang 1,2; Gong, Ningqiang 5,6,7; Zhang, Jianhua1,2 ; Li, Ziqing 2; Cao, Feng 4; Wang, Xiangcheng 3; Liang, Xing-Jie 5,6,7; Jiang, Huaidong1,2
	2017-12
发表期刊	BIOMEDICAL OPTICS EXPRESS
ISSN	2156-7085
卷号	8 期号:12 页码:5825-5833
发表状态	已发表
DOI	10.1364/BOE.8.005825
摘要	Cardiovascular diseases arc closely related to structural blood capillaries lesions. Herein, microscopic investigations of mouse blood capillaries were performed at multiple spatial resolution by using synchrotron X-ray in-line phase contrast tomography and scanning transmission X-ray microscopy (STXM). The chemically fixed blood capillaries without any contrast agents were selected. For the first time, a periodic bamboo-shaped structure was observed at nanoscale resolution by STXM, and the three-dimensional tomographic slices at sub-micrometer resolution further confirmed the periodic wave profile of the blood capillaries. Then, a periodic microstructural model was suggested based on the microscopic images. By using high-performance imaging techniques, this work provides a better understanding of the relationship between the structure and function of blood capillaries, will be helpful in elucidating the causes of cardiovascular system diseases. (C) 2017 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
收录类别	SCI ; EI
语种	英语
资助项目	Natural Science Foundation of China (NSFC)[31430031] ; Natural Science Foundation of China (NSFC)[31630027] ; Natural Science Foundation of China (NSFC)[U1332118]
WOS研究方向	Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000417583800036
出版者	OPTICAL SOC AMER
EI入藏号	20175004523330
EI主题词	Blood ; Blood vessels ; Capillarity ; Cardiovascular system ; Imaging techniques ; Periodic structures ; Tomography
EI分类号	Biomedical Engineering:461.1 ; Biological Materials and Tissue Engineering:461.2 ; Fluid Flow, General:631.1 ; Imaging Techniques:746 ; Atomic and Molecular Physics:931.3
WOS关键词	COMPUTED-TOMOGRAPHY ; HIGH-RESOLUTION ; ANGIOGENESIS ; NANOPARTICLES ; VASCULATURE ; DISEASE
原始文献类型	Article
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/14253
专题	大科学中心_PI研究组_江怀东组硬x射线自由电子激光装置项目
通讯作者	Jiang, Huaidong
作者单位	1.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China 2.Shandong Univ, State Key Lab Crystal Mat, Jinan 250100, Shandong, Peoples R China 3.Inspur Int Ltd, Dept Data & Business Anal Prod, Jinan 250101, Shandong, Peoples R China 4.Chinese Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing 100853, Peoples R China 5.Chinese Acad Sci, Lab Controllable Nanopharmaceut, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 6.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 7.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	物质科学与技术学院
通讯作者单位	物质科学与技术学院
第一作者的第一单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Yao, Shengkun,Zong, Yunbing,Huang, Xu,et al. Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis[J]. BIOMEDICAL OPTICS EXPRESS,2017,8(12):5825-5833.
APA	Yao, Shengkun.,Zong, Yunbing.,Huang, Xu.,Liu, Yang.,Gong, Ningqiang.,...&Jiang, Huaidong.(2017).Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis.BIOMEDICAL OPTICS EXPRESS,8(12),5825-5833.
MLA	Yao, Shengkun,et al."Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis".BIOMEDICAL OPTICS EXPRESS 8.12(2017):5825-5833.