Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
Wang, Chen1; Lin, Haifan2,3
2021-01-08
发表期刊GENOME BIOLOGY
ISSN1474-760X
卷号22期号:1页码:#VALUE!
DOI10.1186/s13059-020-02221-x
摘要PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known for their function in silencing transposons and germline development by partnering with small noncoding RNAs called PIWI-interacting RNAs (piRNAs). However, recent studies have revealed multifaceted roles of the PIWI-piRNA pathway in regulating the expression of other major classes of RNAs in germ cells. In this review, we summarize how PIWI proteins and piRNAs regulate the expression of many disparate RNAs, describing a highly complex global genomic regulatory relationship at the RNA level through which piRNAs functionally connect all major constituents of the genome in the germline.
URL查看原文
收录类别SCI ; SCIE
语种英语
WOS研究方向Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS类目Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS记录号WOS:000609225600002
出版者BMC
原始文献类型Review
引用统计
文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/125900
专题免疫化学研究所_特聘教授组_干细胞生物学实验室
通讯作者Lin, Haifan
作者单位1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China;
2.Yale Univ, Sch Med, Yale Stem Cell Ctr, New Haven, CT 06519 USA;
3.Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06519 USA
第一作者单位免疫化学研究所
第一作者的第一单位免疫化学研究所
推荐引用方式
GB/T 7714
Wang, Chen,Lin, Haifan. Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs[J]. GENOME BIOLOGY,2021,22(1):#VALUE!.
APA Wang, Chen,&Lin, Haifan.(2021).Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs.GENOME BIOLOGY,22(1),#VALUE!.
MLA Wang, Chen,et al."Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs".GENOME BIOLOGY 22.1(2021):#VALUE!.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
个性服务
查看访问统计
谷歌学术
谷歌学术中相似的文章
[Wang, Chen]的文章
[Lin, Haifan]的文章
百度学术
百度学术中相似的文章
[Wang, Chen]的文章
[Lin, Haifan]的文章
必应学术
必应学术中相似的文章
[Wang, Chen]的文章
[Lin, Haifan]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 10.1186@s13059-020-02221-x.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。