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A structural view of the conserved domain of rice stress-responsive NAC1 | |
2011 | |
发表期刊 | PROTEIN & CELL |
ISSN | 1674-800X |
EISSN | 1674-8018 |
卷号 | 2期号:1页码:55-63 |
发表状态 | 已发表 |
DOI | 10.1007/s13238-011-1010-9 |
摘要 | The importance of NAC (named as NAM, ATAF1, 2, and CUC2) proteins in plant development, transcription regulation and regulatory pathways involving protein-protein interactions has been increasingly recognized. We report here the high resolution crystal structure of SNAC1 (stress-responsive NAC) NAC domain at 2.5 angstrom. Although the structure of the SNAC1 NAC domain shares a structural similarity with the reported structure of the ANAC NAC1 domain, some key features, especially relating to two loop regions which potentially take the responsibility for DNA-binding, distinguish the SNAC1 NAC domain from other reported NAC structures. Moreover, the dimerization of the SNAC1 NAC domain is demonstrated by both soluble and crystalline conditions, suggesting this dimeric state should be conserved in this type of NAC family. Additionally, we discuss the possible NAC-DNA binding model according to the structure and reported biological evidences. |
关键词 | stress-responsive NAC 1 NAC family DNA binding rice crystal structure |
URL | 查看原文 |
收录类别 | SCI |
WOS研究方向 | Cell Biology |
WOS类目 | Cell Biology |
WOS记录号 | WOS:000310519400009 |
WOS关键词 | TRANSCRIPTION FACTOR FAMILY ; WIDE COMPARATIVE-ANALYSIS ; SECONDARY WALL SYNTHESIS ; NO-APICAL-MERISTEM ; MOLECULAR CHARACTERIZATION ; COMPREHENSIVE ANALYSIS ; FUNCTIONAL-ANALYSIS ; DIRECT TARGET ; GENE FAMILY ; ARABIDOPSIS |
原始文献类型 | Article |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/120069 |
专题 | 个人在本单位外知识产出 |
通讯作者 | Xiong, Lizhong; Lou, Zhiyong |
作者单位 | 1.Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Natl Ctr Plant Gene Res Wuhan, Wuhan 430070, Peoples R China 2.Tsinghua Univ, Struct Biol Lab, Beijing 100084, Peoples R China 3.Nankai Univ, Coll Life Sci, Tianjin 300071, Peoples R China 4.Nankai Univ, Tianjin State Lab Prot Sci, Tianjin 300071, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Qingfeng,Wang, Quan,Xiong, Lizhong,et al. A structural view of the conserved domain of rice stress-responsive NAC1[J]. PROTEIN & CELL,2011,2(1):55-63. |
APA | Chen, Qingfeng,Wang, Quan,Xiong, Lizhong,&Lou, Zhiyong.(2011).A structural view of the conserved domain of rice stress-responsive NAC1.PROTEIN & CELL,2(1),55-63. |
MLA | Chen, Qingfeng,et al."A structural view of the conserved domain of rice stress-responsive NAC1".PROTEIN & CELL 2.1(2011):55-63. |
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