Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation
Hu, Xiao; Xiao, Guohua; Zheng, Peng; Shang, Yanfang; Su, Yao; Zhang, Xinyu; Liu, Xingzhong; Zhan, Shuai; St Leger, Raymond J.; Wang, Chengshu
2014
Source PublicationPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN0027-8424
Volume111Issue:47Pages:16796-1681
Status已发表
DOI10.1073/pnas.1412662111
Abstract

Much remains unknown regarding speciation. Host-pathogen interactions are a major driving force for diversification, but the genomic basis for speciation and host shifting remains unclear. The fungal genus Metarhizium contains species ranging from specialists with very narrow host ranges to generalists that attack a wide range of insects. By genomic analyses of seven species, we demonstrated that generalists evolved from specialists via transitional species with intermediate host ranges and that this shift paralleled insect evolution. We found that specialization was associated with retention of sexuality and rapid evolution of existing protein sequences whereas generalization was associated with protein-family expansion, loss of genome-defense mechanisms, genome restructuring, horizontal gene transfer, and positive selection that accelerated after reinforcement of reproductive isolation. These results advance understanding of speciation and genomic signatures that underlie pathogen adaptation to hosts.

KeywordMetarhizium speciation transitional species host specificity genomic features
URL查看原文
Indexed BySCI
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000345662700043
PublisherNATL ACAD SCIENCES
WOS KeywordMETARHIZIUM-ANISOPLIAE ; BIOCONTROL AGENTS ; FILAMENTOUS FUNGI ; ORIGIN ; EVOLUTION ; GENE ; PHYLOGENIES ; MECHANISMS ; RESPONSES ; FUSARIUM
Original Document TypeArticle
Citation statistics
Cited Times:167[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttps://kms.shanghaitech.edu.cn/handle/2MSLDSTB/119750
Collection个人在本单位外知识产出
Corresponding AuthorWang, Chengshu
Affiliation1.Chinese Acad Sci, Key Lab Insect Dev & Evolutionary Biol, Inst Plant Physiol & Ecol, Shanghai Inst Biol Sci, Shanghai 200032, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100101, Peoples R China
3.Univ Maryland, Dept Entomol, College Pk, MD 20742 USA
Recommended Citation
GB/T 7714
Hu, Xiao,Xiao, Guohua,Zheng, Peng,et al. Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2014,111(47):16796-1681.
APA Hu, Xiao.,Xiao, Guohua.,Zheng, Peng.,Shang, Yanfang.,Su, Yao.,...&Wang, Chengshu.(2014).Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,111(47),16796-1681.
MLA Hu, Xiao,et al."Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111.47(2014):16796-1681.
Files in This Item: Download All
File Name/Size DocType Version Access License
10.1073@pnas.1412662(1184KB)期刊论文出版稿开放获取UnknownView Download
Related Services
Usage statistics
Scholar Google
Similar articles in Scholar Google
[Hu, Xiao]'s Articles
[Xiao, Guohua]'s Articles
[Zheng, Peng]'s Articles
Baidu academic
Similar articles in Baidu academic
[Hu, Xiao]'s Articles
[Xiao, Guohua]'s Articles
[Zheng, Peng]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Hu, Xiao]'s Articles
[Xiao, Guohua]'s Articles
[Zheng, Peng]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 10.1073@pnas.1412662111.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.