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Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation | |
2014 | |
发表期刊 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
ISSN | 0027-8424 |
卷号 | 111期号:47页码:16796-1681 |
发表状态 | 已发表 |
DOI | 10.1073/pnas.1412662111 |
摘要 | Much remains unknown regarding speciation. Host-pathogen interactions are a major driving force for diversification, but the genomic basis for speciation and host shifting remains unclear. The fungal genus Metarhizium contains species ranging from specialists with very narrow host ranges to generalists that attack a wide range of insects. By genomic analyses of seven species, we demonstrated that generalists evolved from specialists via transitional species with intermediate host ranges and that this shift paralleled insect evolution. We found that specialization was associated with retention of sexuality and rapid evolution of existing protein sequences whereas generalization was associated with protein-family expansion, loss of genome-defense mechanisms, genome restructuring, horizontal gene transfer, and positive selection that accelerated after reinforcement of reproductive isolation. These results advance understanding of speciation and genomic signatures that underlie pathogen adaptation to hosts. |
关键词 | Metarhizium speciation transitional species host specificity genomic features |
URL | 查看原文 |
收录类别 | SCI |
WOS研究方向 | Science & Technology - Other Topics |
WOS类目 | Multidisciplinary Sciences |
WOS记录号 | WOS:000345662700043 |
出版者 | NATL ACAD SCIENCES |
WOS关键词 | METARHIZIUM-ANISOPLIAE ; BIOCONTROL AGENTS ; FILAMENTOUS FUNGI ; ORIGIN ; EVOLUTION ; GENE ; PHYLOGENIES ; MECHANISMS ; RESPONSES ; FUSARIUM |
原始文献类型 | Article |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/119750 |
专题 | 个人在本单位外知识产出 |
通讯作者 | Wang, Chengshu |
作者单位 | 1.Chinese Acad Sci, Key Lab Insect Dev & Evolutionary Biol, Inst Plant Physiol & Ecol, Shanghai Inst Biol Sci, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100101, Peoples R China 3.Univ Maryland, Dept Entomol, College Pk, MD 20742 USA |
推荐引用方式 GB/T 7714 | Hu, Xiao,Xiao, Guohua,Zheng, Peng,et al. Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2014,111(47):16796-1681. |
APA | Hu, Xiao.,Xiao, Guohua.,Zheng, Peng.,Shang, Yanfang.,Su, Yao.,...&Wang, Chengshu.(2014).Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,111(47),16796-1681. |
MLA | Hu, Xiao,et al."Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111.47(2014):16796-1681. |
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