The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3
2012
Source PublicationCELL RESEARCH
ISSN1001-0602
Volume22Issue:12Pages:1666-168
Status已发表
DOI10.1038/cr.2012.151
Abstract

Increased crop yields are required to support rapid population growth worldwide. Grain weight is a key component of rice yield, but the underlying molecular mechanisms that control it remain elusive. Here, we report the cloning and characterization of a new quantitative trait locus (QTL) for the control of rice grain length, weight and yield. This locus, GL3.1, encodes a protein phosphatase kelch (PPKL) family - Ser/Thr phosphatase. GL3.1 is a member of the large grain WY3 variety, which is associated with weaker dephosphorylation activity than the small grain FAZ1 variety. GL3.1-WY3 influences protein phosphorylation in the spikelet to accelerate cell division, thereby resulting in longer grains and higher yields. Further studies have shown that GL3.1 directly dephosphorylates its substrate, Cyclin-T1; 3, which has only been rarely studied in plants. The downregulation of Cyclin-T1; 3 in rice resulted in a shorter grain, which indicates a novel function for Cyclin-T in cell cycle regulation. Our findings suggest a new mechanism for the regulation of grain size and yield that is driven through a novel phosphatase-mediated process that affects the phosphorylation of Cyclin-T1; 3 during cell cycle progression, and thus provide new insight into the mechanisms underlying crop seed development. We bred a new variety containing the natural GL3.1 allele that demonstrated increased grain yield, which indicates that GL3.1 is a powerful tool for breeding high-yield crops.

KeywordQTL cell cycle yield phosphatise Cyclin T
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Indexed BySCI
WOS Research AreaCell Biology
WOS SubjectCell Biology
WOS IDWOS:000311951900010
PublisherINST BIOCHEMISTRY & CELL BIOLOGY
WOS KeywordNATURAL VARIATION ; SERINE/THREONINE PHOSPHATASES ; PROTEIN PHOSPHATASES ; SACCHAROMYCES-CEREVISIAE ; PLANT ARCHITECTURE ; REPEAT DOMAINS ; MAJOR QTL ; ARABIDOPSIS ; FAMILY ; DOMESTICATION
Original Document TypeArticle
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Document Type期刊论文
Identifierhttps://kms.shanghaitech.edu.cn/handle/2MSLDSTB/119706
Collection个人在本单位外知识产出
Corresponding AuthorGao, Ji-Ping; Lin, Hong-Xuan
Affiliation
1.Chinese Acad Sci, Natl Key Lab Plant Mol Genet, Shanghai Inst Biol Sci, Shanghai Inst Plant Physiol & Ecol, Shanghai 200032, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Plant Physiol & Ecol, Natl Ctr Plant Gene Res Shanghai, Shanghai 200032, Peoples R China
3.Chinese Univ Hong Kong, Ctr Cell & Dev Biol, Sch Life Sci, Shatin, Hong Kong, Peoples R China
Recommended Citation
GB/T 7714
Qi, Peng,Lin, You-Shun,Song, Xian-Jun,et al. The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3[J]. CELL RESEARCH,2012,22(12):1666-168.
APA Qi, Peng.,Lin, You-Shun.,Song, Xian-Jun.,Shen, Jin-Bo.,Huang, Wei.,...&Lin, Hong-Xuan.(2012).The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3.CELL RESEARCH,22(12),1666-168.
MLA Qi, Peng,et al."The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3".CELL RESEARCH 22.12(2012):1666-168.
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