Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes

doi:10.1016/j.pt.2020.01.006

	Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes
	Aphasizheva, Inna 1; Alfonzo, Juan 2; Carnes, Jason 3; Cestari, Igor 4; Cruz-Reyes, Jorge 5; Goeringer, H. Ulrich 6; Hajduk, Stephen 7; Lukes, Julius 8,9; Madison-Antenucci, Susan 10; Maslov, Dmitri A.11; McDermott, Suzanne M.3; Ochsenreiter, Torsten 12; Read, Laurie K.13; Salavati, Reza 4; Schnaufer, Achim 14; Schneider, Andre 15; Simpson, Larry 16; Stuart, Kenneth 3; Yurchenko, Vyacheslav 17,20; Zhou, Z. Hong 16; Zikova, Alena 8,9; Zhang, Liye18 ; Zimmer, Sara 19; Aphasizhev, Ruslan 1
	2020-04
发表期刊	TRENDS IN PARASITOLOGY (IF:7.0[JCR-2023],8.1[5-Year])
ISSN	1471-4922
EISSN	1471-5007
卷号	36 期号:4 页码:337-355
发表状态	已发表
DOI	10.1016/j.pt.2020.01.006
摘要	Trypanosoma brucei spp. cause African human and animal trypanosomiasis, a burden on health and economy in Africa. These hemoflagellates are distinguished by a kinetoplast nucleoid containing mitochondrial DNAs of two kinds: maxicircles encoding ribosomal RNAs (rRNAs) and proteins and minicircles bearing guide RNAs (gRNAs) for mRNA editing. All RNAs are produced by a phage-type RNA polymerase as 3' extended precursors, which undergo exonucleolytic trimming. Most pre-mRNAs proceed through 3' adenylation, uridine insertion/deletion editing, and 3' A/U-tailing. The rRNAs and gRNAs are 3' uridylated. Historically, RNA editing has attracted major research effort, and recently essential pre- and postediting processing events have been discovered. Here, we classify the key players that transform primary transcripts into mature molecules and regulate their function and turnover.
收录类别	SCI ; SCIE
语种	英语
资助项目	ERC[CZ LL1601]
WOS研究方向	Parasitology
WOS类目	Parasitology
WOS记录号	WOS:000520157800005
出版者	ELSEVIER SCI LTD
WOS关键词	PENTATRICOPEPTIDE REPEAT PROTEINS ; EDITING-ASSOCIATED PROTEIN-1 ; URIDYLYL TRANSFERASE TUTASE ; EDITOSOME-LIKE COMPLEX ; BLOOD-STREAM FORM ; LIFE-CYCLE STAGES ; MESSENGER-RNA ; GUIDE-RNA ; BINDING COMPLEX ; LEISHMANIA-TARENTOLAE
原始文献类型	Review
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/119181
专题	生命科学与技术学院_PI研究组_张力烨组
通讯作者	Aphasizheva, Inna
作者单位	1.Boston Univ, Dept Mol & Cell Biol, Med Campus, Boston, MA 02118 USA 2.Ohio State Univ, Dept Microbiol, Columbus, OH 43210 USA 3.Seattle Childrens Res Inst, Ctr Global Infect Dis Res, Seattle, WA 98109 USA 4.McGill Univ, Inst Parasitol, 21,111 Lakeshore Rd, Ste Anne De Bellevue, PQ H9X 3V9, Canada 5.Texas A&M Univ, Dept Biochem & Biophys, College Stn, TX 77843 USA 6.Tech Univ Darmstadt, Dept Mol Genet, D-64287 Darmstadt, Germany 7.Univ Georgia, Dept Biochem & Mol Biol, Athens, GA 30602 USA 8.Univ South Bohemia, Inst Parasitol, Biol Ctr, Czech Acad Sci, Ceske Budejovice, Budweis, Czech Republic 9.Univ South Bohemia, Fac Sci, Ceske Budejovice, Budweis, Czech Republic 10.New York State Dept Hlth, Wadsworth Ctr, Parasitol Lab, Albany, NY 12201 USA 11.Univ Calif Riverside, Dept Mol Cell & Syst Biol, Riverside, CA 92521 USA 12.Univ Bern, Inst Cell Biol, Baltzerstr 4, CH-3012 Bern, Switzerland 13.Univ Buffalo, Jacobs Sch Medidne & Biomed Sdences, Dept Microbiol & Immunol, Buffalo, NY 14203 USA 14.Univ Edinburgh, Inst Immunol & Infect Res, Edinburgh EH9 3FL, Midlothian, Scotland 15.Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland 16.Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA 17.Univ Ostrava, Fac Sci, Life Sci Res Ctr, Ostrava, Czech Republic 18.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 19.Univ Minnesota, Med Sch, Duluth Campus, Duluth, MN 55812 USA 20.Sechenov Univ, Martsinovsky Inst Med Parasitol, Moscow, Russia
推荐引用方式 GB/T 7714	Aphasizheva, Inna,Alfonzo, Juan,Carnes, Jason,et al. Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes[J]. TRENDS IN PARASITOLOGY,2020,36(4):337-355.
APA	Aphasizheva, Inna.,Alfonzo, Juan.,Carnes, Jason.,Cestari, Igor.,Cruz-Reyes, Jorge.,...&Aphasizhev, Ruslan.(2020).Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.TRENDS IN PARASITOLOGY,36(4),337-355.
MLA	Aphasizheva, Inna,et al."Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes".TRENDS IN PARASITOLOGY 36.4(2020):337-355.