Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality

doi:10.1021/acs.nanolett.9b02324

	Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality
	Li, Yingfeng1,2,3 ; Li, Ke1,2 ; Wang, Xinyu1 ; An, Bolin1 ; Cui, Mengkui1 ; Pu, Jiahua1 ; Wei, Shicao1 ; Xue, Shuai 4,5; Ye, Haifeng 4,5; Zhao, Yanhua 6; Liu, Minjie 6; Wang, Zuankai 6; Zhong, Chao1
	2019-12
发表期刊	NANO LETTERS (IF:9.6[JCR-2023],10.1[5-Year])
ISSN	1530-6984
EISSN	1530-6992
卷号	19 期号:12 页码:8399-8408
发表状态	已发表
DOI	10.1021/acs.nanolett.9b02324
摘要	The precise manipulation, localization, and assembly of biological and bioinspired molecules into organized structures have greatly promoted material science and bionanotechnology. Further technological innovation calls for new patternable soft materials with the long-sought qualities of environmental tolerance and functional flexibility. Here, we report a patterned amyloid material (PAM) platform for producing hierarchically ordered structures that integrate these material attributes. This platform, combining soft lithography with generic amyloid monomer inks (consisting of genetically engineered biofilm proteins dissolved in hexafluoroisopropanol), along with methanol-assisted curing, enables the spatially controlled deposition and in situ reassembly of amyloid monomers. The resulting patterned structures exhibit spectacular chemical and thermal stability and mechanical robustness under harsh conditions. The PAMs can be programmed for a vast array of multilevel functionalities, including anchoring nanoparticles, enabling diverse fluorescent protein arrays, and serving as self-supporting porous sheets for cellular growth. This PAM platform will not only drive innovation in biomanufacturing but also broaden the applications of patterned soft architectures in optics, electronics, biocatalysis, analytical regents, cell engineering, medicine, and other areas.
关键词	Biofilm genetic engineering soft lithography patterning
收录类别	SCI ; SCIE ; EI
语种	英语
资助项目	National Natural Science Foundation of China[U1532127] ; National Natural Science Foundation of China[31570972]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:000502687500007
出版者	AMER CHEMICAL SOC
WOS关键词	PROTEIN ; SILK ; PEPTIDE ; ACTIN ; FIBRONECTIN ; CHITIN ; FILMS
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/104963
专题	物质科学与技术学院_博士生物质科学与技术学院_PI研究组_钟超组物质科学与技术学院_硕士生
通讯作者	Zhong, Chao
作者单位	1.ShanghaiTech Univ, Sch Phys Sci & Technol, Mat & Phys Biol Div, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.East China Normal Univ, Shanghai Key Lab Regulatory Biol, Inst Biomed Sci, Shanghai 200241, Peoples R China 5.East China Normal Univ, Sch Life Sci, Shanghai 200241, Peoples R China 6.City Univ Hong Kong, Dept Mech & Biomed Engn, Hong Kong 999077, Peoples R China
第一作者单位	物质科学与技术学院
通讯作者单位	物质科学与技术学院
第一作者的第一单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Li, Yingfeng,Li, Ke,Wang, Xinyu,et al. Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality[J]. NANO LETTERS,2019,19(12):8399-8408.
APA	Li, Yingfeng.,Li, Ke.,Wang, Xinyu.,An, Bolin.,Cui, Mengkui.,...&Zhong, Chao.(2019).Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality.NANO LETTERS,19(12),8399-8408.
MLA	Li, Yingfeng,et al."Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality".NANO LETTERS 19.12(2019):8399-8408.