An intermediate cell state allows rerouting of cell fate

doi:10.1074/jbc.H117.812537

	An intermediate cell state allows rerouting of cell fate
	Wang, Xiukun 1,2; Li, Jinsong1,2,3
	2017-11-17
发表期刊	JOURNAL OF BIOLOGICAL CHEMISTRY
ISSN	0021-9258
卷号	292 期号:46 页码:19133-19134
发表状态	已发表
DOI	10.1074/jbc.H117.812537
摘要	Somatic cell reprogramming into pluripotent stem cells using transcriptional factors or chemical compounds has been shown to include an intermediate cell state with epithelial features. Two recent papers show that this intermediate state can be redirected to create other differentiated cell typesspecifically hepatocytes and neuronsusing chemical cocktails. These results shed new light on a critical intermediate in cell fate conversion with mechanistic and practical implications.
收录类别	SCI ; EI
语种	英语
资助项目	Shanghai Municipal Commission for Science and Technology[16JC1420500] ; Shanghai Municipal Commission for Science and Technology[17JC1400900]
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:000415848000036
出版者	AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
EI入藏号	20174704437312
EI主题词	Cells ; Chemical compounds ; Stem cells
EI分类号	Biological Materials and Tissue Engineering:461.2
WOS关键词	XEN-LIKE STATE
原始文献类型	Editorial Material
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/10057
专题	生命科学与技术学院_特聘教授组_李劲松组
通讯作者	Li, Jinsong
作者单位	1.Univ Chinese Acad Sci, Chinese Acad Sci, State Key Lab Cell Biol, CAS Ctr Excellence Mol Cell Sci, 320 Yueyang Rd, Shanghai 200031, Peoples R China 2.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Key Lab Mol Androl, Inst Biochem & Cell Biol, 320 Yueyang Rd, Shanghai 200031, Peoples R China 3.Shanghai Tech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Wang, Xiukun,Li, Jinsong. An intermediate cell state allows rerouting of cell fate[J]. JOURNAL OF BIOLOGICAL CHEMISTRY,2017,292(46):19133-19134.
APA	Wang, Xiukun,&Li, Jinsong.(2017).An intermediate cell state allows rerouting of cell fate.JOURNAL OF BIOLOGICAL CHEMISTRY,292(46),19133-19134.
MLA	Wang, Xiukun,et al."An intermediate cell state allows rerouting of cell fate".JOURNAL OF BIOLOGICAL CHEMISTRY 292.46(2017):19133-19134.