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Population genomics of East Asian ethnic groups | |
2020-12-08 | |
发表期刊 | HEREDITAS |
ISSN | 1601-5223 |
卷号 | 157期号:1 |
发表状态 | 已发表 |
DOI | 10.1186/s41065-020-00162-w |
摘要 | East Asia constitutes one-fifth of the global population and exhibits substantial genetic diversity. However, genetic investigations on populations in this region have been largely under-represented compared with European populations. Nonetheless, the last decade has seen considerable efforts and progress in genome-wide genotyping and whole-genome sequencing of the East-Asian ethnic groups. Here, we review the recent studies in terms of ancestral origin, population relationship, genetic differentiation, and admixture of major East- Asian groups, such as the Chinese, Korean, and Japanese populations. We mainly focus on insights from the whole-genome sequence data and also include the recent progress based on mitochondrial DNA (mtDNA) and Y chromosome data. We further discuss the evolutionary forces driving genetic diversity in East-Asian populations, and provide our perspectives for future directions on population genetics studies, particularly on underrepresented indigenous groups in East Asia. |
关键词 | Population genetics Whole-genome sequence data East Asian Evolutionary forces |
URL | 查看原文 |
收录类别 | SCI ; SCIE |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China (NSFC)[31525014][32030020][91731303][31771388][31961130380][32041008] ; UK Royal Society-Newton Advanced Fellowship[NAF\R1\191094] ; Key Research Program of Frontier Sciences[QYZDJ-SSW-SYS009] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB38000000] ; Shanghai Municipal Science and Technology Major Project[2017SHZDZX01] |
WOS研究方向 | Genetics & Heredity |
WOS类目 | Genetics & Heredity |
WOS记录号 | WOS:000597264700001 |
出版者 | BMC |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/124774 |
专题 | 生命科学与技术学院_特聘教授组_徐书华组 |
通讯作者 | Xu, Shuhua |
作者单位 | 1.Univ Chinese Acad Sci, Key Lab Computat Biol, CAS MPG Partner Inst Computat Biol, Shanghai Inst Nutr & Hlth,Chinese Acad Sci, Shanghai 200031, Peoples R China 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 3.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming 650223, Yunnan, Peoples R China 4.Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Shanghai 200438, Peoples R China |
通讯作者单位 | 生命科学与技术学院 |
推荐引用方式 GB/T 7714 | Pan, Ziqing,Xu, Shuhua. Population genomics of East Asian ethnic groups[J]. HEREDITAS,2020,157(1). |
APA | Pan, Ziqing,&Xu, Shuhua.(2020).Population genomics of East Asian ethnic groups.HEREDITAS,157(1). |
MLA | Pan, Ziqing,et al."Population genomics of East Asian ethnic groups".HEREDITAS 157.1(2020). |
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