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Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6489, 页码: 428-+
Authors:  Yu, Jing;  Gimenez, Luis E.;  Hernandez, Ciria C.;  Wu, Yiran;  Wein, Ariel H.;  Han, Gye Won;  McClary, Kyle;  Mittal, Sanraj R.;  Burdsall, Kylie;  Stauch, Benjamin;  Wu, Lijie;  Stevens, Sophia N.;  Peisley, Alys;  Williams, Savannah Y.;  Chen, Valerie;  Millhauser, Glenn L.;  Zhao, Suwen;  Cone, Roger D.;  Stevens, Raymond C.
Favorite  |  View/Download:4/0  |  Submit date:2020/05/14
The structural study of mutation-induced inactivation of human muscarinic receptor M4 期刊论文
IUCRJ, 2020, 卷号: 7, 页码: 294-305
Authors:  Wang, Jingjing;  Wu, Meng;  Wu, Lijie;  Xu, Yueming;  Li, Fei;  Wu, Yiran;  Popov, Petr;  Wang, Lin;  Bai, Fang;  Zhao, Suwen;  Liu, Zhi-Jie;  Hua, Tian
Favorite  |  View/Download:32/0  |  Submit date:2020/04/08
Metabolic Reprogramming in Cancer Is Induced to Increase Proton Production 期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 5, 页码: 1143-1155
Authors:  Sun, Huiyan;  Zhou, Yi;  Skaro, Michael Francis;  Wu, Yiran;  Qu, Zexing;  Mao, Fenglou;  Zhao, Suwen;  Xu, Ying
Favorite  |  View/Download:13/0  |  Submit date:2020/03/27
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
Authors:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye;  Cao, Haijie;  Huang, Xi-Ping;  Cai, Xiaoqing;  Sun, Wen;  Ye, Na;  Xu, Yueming;  Peng, Yao;  Zhao, Suwen;  Liu, Zhi-Jie;  Zhong, Guisheng;  Wang, Ming-Wei;  Shui, Wenqing
Favorite  |  View/Download:16/0  |  Submit date:2020/03/28
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-G(i) Complex Structures 期刊论文
CELL, 2020, 卷号: 180, 期号: 4, 页码: 655-+
Authors:  Hua, Tian;  Li, Xiaoting;  Wu, Lijie;  Iliopoulos-Tsoutsouvas, Christos;  Wang, Yuxia;  Wu, Meng;  Shen, Ling;  Johnston, Christina A.;  Nikas, Spyros P.;  Song, Feng;  Song, Xiyong;  Yuan, Shuguang;  Sun, Qianqian;  Wu, Yiran;  Jiang, Shan;  Grim, Travis W.;  Benchama, Othman;  Stahl, Edward L.;  Zvonok, Nikolai;  Zhao, Suwen;  Bohn, Laura M.;  Makriyannis, Alexandros;  Liu, Zhi-Jie
Favorite  |  View/Download:22/0  |  Submit date:2020/03/16
Structural basis of ligand recognition and self-activation of orphan GPR52 期刊论文
NATURE, 2020
Authors:  Lin, Xi;  Li, Mingyue;  Wang, Niandong;  Wu, Yiran;  Luo, Zhipu;  Guo, Shimeng;  Han, Gye-Won;  Li, Shaobai;  Yue, Yang;  Wei, Xiaohu;  Xie, Xin;  Chen, Yong;  Zhao, Suwen;  Wu, Jian;  Lei, Ming;  Xu, Fei
Favorite  |  View/Download:22/0  |  Submit date:2020/03/16
Database Resources of the National Genomics Data Center in 2020 期刊论文
NUCLEIC ACIDS RESEARCH, 2020, 卷号: 48, 期号: D1, 页码: D24-D33
Authors:  Zhang, Zhang;  Zhao, Wenming;  Xiao, Jingfa;  Bao, Yiming;  He, Shunmin;  Zhang, Guoqing;  Li, Yixue;  Zhao, Guoping;  Chen, Runsheng;  Gao, Yang;  Zhang, Chao;  Yuan, Liyun;  Xu, Shuhua;  Ning, Zhilin;  Lu, Yan;  Zeng, Jingyao;  Yuan, Na;  Zhu, Junwei;  Pan, Mengyu;  Zhang, Hao;  Wang, Qi;  Shi, Shuo;  Jiang, Meiye;  Lu, Mingming;  Qian, Qiheng;  Gao, Qianwen;  Shang, Yunfei;  Wang, Jinyue;  Du, Zhenglin;  Tian, Dongmei;  Wang, Pei;  Tang, Bixia;  Li, Cuiping;  Teng, Xufei;  Liu, Xiaonan;  Zou, Dong;  Song, Shuhui;  Xiong, Zhuang;  Li, Mengwei;  Yang, Fei;  Ma, Yingke;  Sang, Jian;  Li, Zhaohua;  Li, Rujiao;  Wang, Zhonghuang;  Zhu, Qianghui;  Li, Xin;  Zhang, Sisi;  Kang, Hailong;  Dong, Lili;  Ying, Cui;  Duan, Guangya;  Li, Menghua;  Zhi, Xiaoyang;  Ling, Yunchao;  Cao, Ruifang;  Jiang, Zhao;  Zhou, Haokui;  Lv, Daqing;  Liu, Wan;  Klenk, Hans-Peter;  Zhang, Yadong;  Zhang, Zhewen;  Chen, Tingting;  Chen, Xu;  Wang, Yanqing;  Wu, Song;  Gong, Zheng;  Chen, Meili;  Fang, Shuangsang;  Zhang, Lili;  Guo, Jincheng;  Niu, Yiwei;  Wu, Yang;  Li, Hui;  Zhao, Lianhe;  Li, Xiyuan;  Teng, Xueyi;  Sun, Xianhui;  Sun, Liang;  Zhao, Yi;  Wang, Jiajia;  Zhang, Peng;  Li, Yanyan;  Zheng, Yu;  Chen, Xiaomin;  Xue, Hua;  Teng, Yiheng;  Kang, Quan;  Hao, Yajing;  Cao, Jiabao;  Liu, Lin;  Li, Zhao;  Li, Qianpeng;  Du, Qiang;  Abbasi, Amir A.;  Shireen, Huma;  Pervaiz, Nashaiman;  Batool, Fatima;  Raza, Rabail Z.;  Ma, Lina;  Niu, Guangyi;  Zhang, Yuansheng;  Zhu, Tongtong;  Hao, Lili;  Wang, Guoliang;  Yan, Jun;  Li, Chen;  Wang, Zhennan;  Wang, Xiangfeng;  Li, Zhonghai;  Zhang, Yang;  Wang, Houling;  Zhang, Yi;  Xia, Xinli;  Guo, Hongwei;  Zhu, Junwen;  Zhou, Qing;  Kang, Hongen;  Lan, Li;  Zhang, Xin;  Xue, Yongbiao;  Sun, Yubin;  Zhai, Shuang;  Yu, Lei;  Sun, Mingyuan;  Chen, Huanxin;  Hu, Hui;  Guo, An-Yuan;  Lin, Shaofeng;  Xue, Yu;  Wang, Chenwei;  Ning, Wanshan;  Zhang, Xinxin;  Xiao, Yun;  Li, Xia;  Tu, Yiran;  Wu, Wanying;  Ji, Peifeng;  Zhao, Fangqing;  Luo, Hao;  Gao, Feng;  Guo, Yaping;  Yuan, Hao;  Zhang, Yong E.;  Zhang, Qiong;  Zhou, Jiaqi;  Huang, Zhou;  Cui, Qinghua;  Miao, Ya-Ru;  Ruan, Chen;  Yuan, Chunhui;  Chen, Ming;  Jin, Jin-Pu;  Tian, Feng;  Gao, Ge;  Shi, Ying;  Yao, Lan;  Li, Xiangshang;  Li, Chuan-Yun;  Tang, Qing;  Peng, Di
Favorite  |  View/Download:3/0  |  Submit date:2020/05/06
Molecular Mechanism for Ligand Recognition and Subtype Selectivity of alpha(2C) Adrenergic Receptor 期刊论文
CELL REPORTS, 2019, 卷号: 29, 期号: 10, 页码: 2936-+
Authors:  Chen, Xiaoyu;  Xu, Yueming;  Qu, Lu;  Wu, Lijie;  Han, Gye Won;  Guo, Yu;  Wu, Yiran;  Zhou, Qingtong;  Sun, Qianqian;  Chu, Cenfeng;  Yang, Jie;  Yang, Liu;  Wang, Quan;  Yuan, Shuguang;  Wang, Ling;  Hu, Tao;  Tao, Houchao;  Sun, Yaping;  Song, Yunpeng;  Hu, Liaoyuan;  Liu, Zhi-Jie;  Stevens, Raymond C.;  Zhao, Suwen;  Wu, Dong;  Zhong, Guisheng
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Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989
Authors:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan;  Zhao, Fei;  Wu, Yiran;  Zhang, Xianjun;  Tan, Qiwen;  Xu, Fei;  Tan, Wenfu;  Xiao, Youli;  Zhao, Suwen;  Tao, Houchao
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Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist 期刊论文
MOLECULAR PHARMACOLOGY, 2019, 卷号: 96, 期号: 5, 页码: 619-628
Authors:  Laprairie, Robert B.;  Vemuri, Kiran;  Stahl, Edward L.;  Korde, Anisha;  Ho, Jo-Hao;  Grim, Travis W.;  Hua, Tian;  Wu, Yiran;  Stevens, Raymond C.;  Liu, Zhi-Jie;  Makriyannis, Alexandros;  Bohn, Laura M.
Adobe PDF(2131Kb)  |  Favorite  |  View/Download:35/1  |  Submit date:2019/10/28