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Efficient Gene Silencing by Adenine Base Editor-Mediated Start Codon Mutation 期刊论文
MOLECULAR THERAPY, 2020, 卷号: 28, 期号: 2, 页码: 431-440
Authors:  Wang, Xinjie;  Liu, Zhiwei;  Li, GuangLei;  Dang, Lu;  Huang, Shisheng;  He, Lei;  Ma, Yu'e;  Li, Cong;  Liu, Ming;  Yang, Guang;  Huang, Xingxu;  Zhou, Fei;  Ma, Xiaodong
Favorite  |  View/Download:12/0  |  Submit date:2020/03/05
Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 2
Authors:  Lu, Zongyang;  Liu, Zhen;  Mao, Wei;  Wang, Xinying;  Zheng, Xiaoguo;  Chen, Shanshan;  Cao, Beibei;  Huang, Shisheng;  Zhang, Xuliang;  Zhou, Tao;  Zhang, Yu;  Huang, Xingxu;  Sun, Qiang;  Li, Jia-Da
Favorite  |  View/Download:7/0  |  Submit date:2020/02/21
Increasing the targeting scope and efficiency of base editing with Proxy-BE strategy 期刊论文
FEBS LETTERS, 2019
Authors:  Liu, Yin;  Li, Guanglei;  Yang, Guang;  Gu, Huifeng;  Huang, Shisheng;  Yu, Wenxia;  Qin, Guizhen;  Liu, Xinyi;  Zhou, Fuling;  Huang, Xingxu;  Wei, Yongchang
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Site-directed RNA editing (SDRE): Off-target effects and their countermeasures 期刊论文
JOURNAL OF GENETICS AND GENOMICS, 2019, 卷号: 46, 期号: 11, 页码: 531-535
Authors:  Mao, Shaoshuai;  Liu, Yajing;  Huang, Shisheng;  Huang, Xingxu;  Chi, Tian
Favorite  |  View/Download:14/0  |  Submit date:2020/02/21
Efficient Generation of Pathogenic A-to-G Mutations in Human Tripronuclear Embryos via ABE-Mediated Base Editing 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2019, 卷号: 17, 页码: 289-296
Authors:  Li, Guanglei;  Liu, Xinyi;  Huang, Shisheng;  Zeng, Yanting;  Yang, Guang;  Lu, Zongyang;  Zhang, Yu;  Ma, Xu;  Wang, Lisheng;  Huang, Xingxu;  Liu, Jianqiao
View  |  Adobe PDF(1676Kb)  |  Favorite  |  View/Download:29/3  |  Submit date:2019/10/28
Developing ABEmax-NG with Precise Targeting and Expanded Editing Scope to Model Pathogenic Splice Site Mutations In Vivo 期刊论文
ISCIENCE, 2019, 卷号: 15, 页码: 640-+
Authors:  Huang, Shisheng;  Liao, Zhaodi;  Li, Xiangyang;  Liu, Zhen;  Li, Guanglei;  Li, Jianan;  Lu, Zongyang;  Zhang, Yu;  Li, Xiajun;  Ma, Xu;  Sun, Qiang;  Huang, Xingxu
Adobe PDF(3140Kb)  |  Favorite  |  View/Download:80/2  |  Submit date:2019/07/01
一种腺嘌呤碱基编辑工具及其用途 专利
专利类型: 发明专利, 公开日期: 2019-07-19
Inventors:  黄诗圣;  李向阳;  黄行许
View  |  Adobe PDF(1247Kb)  |  Favorite  |  View/Download:106/22  |  Submit date:2019/08/30
Carbon-dot-supported atomically dispersed gold as a mitochondrial oxidative stress amplifier for cancer treatment 期刊论文
NATURE NANOTECHNOLOGY, 2019, 卷号: 14, 期号: 4, 页码: 379-+
Authors:  Gong, Ningqiang;  Ma, Xiaowei;  Ye, Xiaoxia;  Zhou, Qunfang;  Chen, Xiaoai;  Tan, Xiaoli;  Yao, Shengkun;  Huo, Shuaidong;  Zhang, Tingbin;  Chen, Shizhu;  Teng, Xucong;  Hu, Xixue;  Yu, Jie;  Gan, Yaling;  Jiang, Huaidong;  Li, Jinghong;  Liang, Xing-Jie
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Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome 期刊论文
CELL RESEARCH, 2019, 卷号: 29, 期号: 2, 页码: 174-176
Authors:  Li, Jianan;  Liu, Zhen;  Huang, Shisheng;  Wang, Xiao;  Li, Guanglei;  Xu, Yuting;  Yu, Wenxia;  Chen, Shanshan;  Zhang, Yu;  Ma, Hanhui;  Ke, Zunfu;  Chen, Jia;  Sun, Qiang;  Huang, Xingxu
Adobe PDF(1267Kb)  |  Favorite  |  View/Download:109/4  |  Submit date:2019/02/15
Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development 期刊论文
CELL REPORTS, 2019, 卷号: 26, 期号: 2, 页码: 302-+
Authors:  Yang, Guang;  Zhou, Changyang;  Wang, Ran;  Huang, Shisheng;  Wei, Yu;  Yang, Xianfa;  Liu, Yajing;  Li, Jianan;  Lu, Zongyang;  Ying, Wenqin;  Li, Xiajun;  Jing, Naihe;  Huang, Xingxu;  Yang, Hui;  Qiao, Yunbo
Adobe PDF(4792Kb)  |  Favorite  |  View/Download:128/2  |  Submit date:2019/01/21