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Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur 期刊论文
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2020
Authors:  Jin, Zhenming;  Zhao, Yao;  Sun, Yuan;  Zhang, Bing;  Wang, Haofeng;  Wu, Yan;  Zhu, Yan;  Zhu, Chen;  Hu, Tianyu;  Du, Xiaoyu;  Duan, Yinkai;  Yu, Jing;  Yang, Xiaobao;  Yang, Xiuna;  Yang, Kailin;  Liu, Xiang;  Guddat, Luke W.;  Xiao, Gengfu;  Zhang, Leike;  Yang, Haitao;  Rao, Zihe
Adobe PDF(4556Kb)  |  Favorite  |  View/Download:13/1  |  Submit date:2020/05/25
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2) 期刊论文
PROTEIN & CELL, 2020
Authors:  Zhang, Lu;  Zhao, Yao;  Gao, Ruogu;  Li, Jun;  Yang, Xiuna;  Gao, Yan;  Zhao, Wei;  Gurcha, Sudagar S.;  Veerapen, Natacha;  Batt, Sarah M.;  Besra, Kajelle Kaur;  Xu, Wenqing;  Bi, Lijun;  Zhang, Xian'en;  Guddat, Luke W.;  Yang, Haitao;  Wang, Quan;  Besra, Gurdyal S.;  Rao, Zihe
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Structures of Cell Wall Arabinosyltransferases With the Anti-Tuberculosis Drug Ethambutol 期刊论文
SCIENCE, 2020
Authors:  Lu Zhang;  Yao Zhao;  Yan Gao;  Lijie Wu;  Ruogu Gao;  Qi Zhang;  Yinan Wang;  Chengyao Wu;  Fangyu Wu;  Sudagar S. Gurcha;  Natacha Veerapen;  Sarah M. Batt;  Wei Zhao;  Ling Qin;  Xiuna Yang;  Manfu Wang;  Yan Zhu;  Bing Zhang;  Lijun Bi;  Xian’en Zhang;  Haitao Yang;  Luke W. Guddat;  Wenqing Xu;  Quan Wang;  Jun Li;  Gurdyal S. Besra;  Zihe Rao
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
SCIENCE, 2020
Authors:  Wenhao Dai;  Bing Zhang;  Xia-Ming Jiang;  Haixia Su;  Jian Li;  Yao Zhao;  Xiong Xie;  Zhenming Jin;  Jingjing Peng;  Fengjiang Liu;  Chunpu Li;  You Li;  Fang Bai;  Haofeng Wang;  Xi Cheng;  Xiaobo Cen;  Shulei Hu;  Xiuna Yang;  Jiang Wang;  Xiang Liu;  Gengfu Xiao;  Hualiang Jiang;  Zihe Rao;  Lei-Ke Zhang;  Yechun Xu;  Haitao Yang;  Hong Liu
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Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
SCIENCE, 2020
Authors:  Yan Gao;  Liming Yan;  Yucen Huang;  Fengjiang Liu;  Yao Zhao;  Lin Cao;  Tao Wang;  Qianqian Sun;  Zhenhua Ming;  Lianqi Zhang;  Ji Ge;  Litao Zheng;  Ying Zhang;  Haofeng Wang;  Yan Zhu;  Chen Zhu;  Tianyu Hu;  Tian Hua;  Bing Zhang;  Xiuna Yang;  Jun Li;  Haitao Yang;  Zhijie Liu;  Wenqing Xu;  Luke W. Guddat;  Quan Wang;  Zhiyong Lou;  Zihe Rao
View  |  Adobe PDF(963Kb)  |  Favorite  |  View/Download:131/20  |  Submit date:2020/04/17
Structure of Mpro from COVID-19 virus and discovery of its inhibitors 期刊论文
NATURE, 2020
Authors:  Zhenming Jin;  Xiaoyu Du;  Yechun Xu;  Yongqiang Deng;  Meiqin Liu;  Yao Zhao;  Bing Zhang;  Xiaofeng Li;  Leike Zhang;  Chao Peng;  Yinkai Duan;  Jing Yu;  Lin Wang;  Kailin Yang;  Fengjiang Liu;  Rendi Jiang;  Xinglou Yang;  Tian You;  Xiaoce Liu;  Xiuna Yang;  Fang Bai;  Hong Liu;  Xiang Liu;  Luke W. Guddat;  Wenqing Xu;  Gengfu Xiao;  Chengfeng Qin;  Zhengli Shi;  Hualiang Jiang;  Zihe Rao;  Haitao Yang
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Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 8, 页码: 4061-4070
Authors:  Yan, Liming;  Qi, Yuanbo;  Ricketson, Derek;  Li, Lei;  Subramanian, Kelly;  Zhao, Jinghua;  Yu, Caiting;  Wu, Lijie;  Sarsam, Reta;  Wong, Melissa;  Lou, Zhiyong;  Rao, Zihe;  Nunnari, Jodi;  Hu, Junjie
Favorite  |  View/Download:10/0  |  Submit date:2020/03/28
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity 期刊论文
NATURE, 2020, 卷号: 577, 期号: 7792, 页码: 682-+
Authors:  Wang, Lin;  Wu, Juehui;  Li, Jun;  Yang, Hua;  Tang, Tianqi;  Liang, Haijiao;  Zuo, Mianyong;  Wang, Jie;  Liu, Haipeng;  Liu, Feng;  Chen, Jianxia;  Liu, Zhonghua;  Wang, Yang;  Peng, Cheng;  Wu, Xiangyang;  Zheng, Ruijuan;  Huang, Xiaochen;  Ran, Yajun;  Rao, Zihe;  Ge, Baoxue
Favorite  |  View/Download:10/0  |  Submit date:2020/02/21
Structural insights into substrate recognition by the type VII secretion system 期刊论文
PROTEIN & CELL, 2019
Authors:  Wang, Shuhui;  Zhou, Kaixuan;  Yang, Xiaolin;  Zhang, Bing;  Zhao, Yao;  Xiao, Yu;  Yang, Xiuna;  Yang, Haitao;  Guddat, Luke W.;  Li, Jun;  Rao, Zihe
View  |  Adobe PDF(4941Kb)  |  Favorite  |  View/Download:52/12  |  Submit date:2019/12/11
Architecture of African swine fever virus and implications for viral assembly 期刊论文
SCIENCE, 2019, 卷号: 366, 期号: 6465, 页码: 640-+
Authors:  Wang, Nan;  Zhao, Dongming;  Wang, Jialing;  Zhang, Yangling;  Wang, Ming;  Gao, Yan;  Li, Fang;  Wang, Jingfei;  Bu, Zhigao;  Rao, Zihe;  Wang, Xiangxi
Adobe PDF(1443Kb)  |  Favorite  |  View/Download:22/1  |  Submit date:2019/12/05