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Comparative genetic architectures of schizophrenia in East Asian and European populations 期刊论文
NATURE GENETICS, 2019, 卷号: 51, 期号: 12, 页码: 1670-+
Authors:  Lam, Max;  Chen, Chia-Yen;  Li, Zhiqiang;  Martin, Alicia R.;  Bryois, Julien;  Ma, Xixian;  Gaspar, Helena;  Ikeda, Masashi;  Benyamin, Beben;  Brown, Brielin C.;  Liu, Ruize;  Zhou, Wei;  Guan, Lili;  Kamatani, Yoichiro;  Kim, Sung-Wan;  Kubo, Michiaki;  Kusumawardhani, Agung A. A. A.;  Liu, Chih-Min;  Ma, Hong;  Periyasamy, Sathish;  Takahashi, Atsushi;  Xu, Zhida;  Yu, Hao;  ZhU, Feng;  Chen, Wei J.;  Faraone, Stephen;  Glatt, Stephen J.;  He, Lin;  Hyman, Steven E.;  Hwu, Hai-Gwo;  McCarro, Steven A.;  Neale, Benjamin M.;  Sklar, Pamela;  Wildenauer, Dieter B.;  Yu, Xin;  Zhang, Dai;  Mowry, Bryan J.;  Lee, Jimmy;  Holmans, Peter;  Xu, Shuhua;  Sullivan, Patrick F.;  Ripke, Stephan;  O'Donovan, Michael C.;  Daly, Mark J.;  Qin, Shengying;  Sham, Pak;  Iwata, Nakao;  Hong, Kyung S.;  Schwab, Sibylle G.;  Yue, Weihua;  Tsuang, Ming;  Liu, Jianjun;  Ma, Xiancang;  Kahn, Rene S.;  Shi, Yongyong;  Huang, Hailiang
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Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
Authors:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun;  Lu, Tian;  Tao, Hongru;  Xiao, Senhao;  Zhang, Fengcai;  Liu, Yu-Chih;  Liu, Rongfeng;  Zhang, Naixia;  Jiang, Hualiang;  Chen, Kaixian;  Zhao, Chunshen;  Luo, Cheng
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Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
Authors:  Tao, Hongru;  Wang, Jun;  Lu, Wenchao;  Zhang, Rukang;  Xie, Yiqian;  Liu, Yu-Chih;  Liu, Rongfeng;  Yue, Liyan;  Chen, Kaixian;  Jiang, Hualiang;  Zhang, Yuanyuan;  Xu, Xiaohui;  Luo, Cheng
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Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
Authors:  Lu, Wenchao;  Xiong, Huan;  Chen, Yu;  Wang, Chen;  Zhang, Hao;  Xu, Pan;  Han, Jie;  Xiao, Senhao;  Ding, Hong;  Chen, Zhifeng;  Lu, Tian;  Wang, Jun;  Zhang, Yuanyuan;  Yue, Liyan;  Liu, Yu-Chih;  Zhang, Chenhua;  Yang, Yaxi;  Jiang, Hualiang;  Chen, Kaixian;  Zhou, Bing;  Luo, Cheng
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Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
Authors:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao;  Lian, Fulin;  Zhang, Naixia;  Ding, Hong;  Zhang, Yuanyuan;  Chen, Kaixian;  Jiang, Hualiang;  Zhang, Chenhua;  Liu, Yu-Chih;  Chen, Shijie;  Luo, Cheng
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Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
Authors:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng;  Zhang, Hao;  Lian, Fulin;  Liu, Yu-Chih;  Zhang, Chenhua;  Ding, Hong;  Chen, Shijie;  Zhang, Naixia;  Zhang, Yuanyuan;  Jiang, Hualiang;  Chen, Kaixian;  Ye, Fei;  Yao, Zhiyi;  Luo, Cheng
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Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 17, 页码: 3648-3661
Authors:  Ye, Yan;  Zhang, Bidong;  Mao, Ruifeng;  Zhang, Chenhua;  Wang, Yulan;  Xing, Jing;  Liu, Yu-Chih;  Luo, Xiaomin;  Ding, Hong;  Yang, Yaxi;  Zhou, Bing;  Jiang, Hualiang;  Chen, Kaixian;  Luo, Cheng;  Zheng, Mingyue
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Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 2, 页码: 342-346
Authors:  Shao, Zhiyuan;  Xu, Pan;  Xu, Wen;  Li, Linjuan;  Liu, Shien;  Zhang, Rukang;  Liu, Yu-Chih;  Zhang, Chenhua;  Chen, Shijie;  Luo, Cheng
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Discovery of Novel Inhibitors Targeting the Menin-Mixed Lineage Leukemia Interface Using Pharmacophore- and Docking-Based Virtual Screening 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 9, 页码: 1847-1855
Authors:  Xu, Yuan;  Yue, Liyan;  Wang, Yulan;  Xing, Jin;  Chen, Zhifeng;  Shi, Zhe;  Liu, Rongfeng;  Liu, Yu-Chih;  Luo, Xiaomin;  Jiang, Hualiang;  Chen, Kaixian;  Luo, Cheng;  Zheng, Mingyue
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Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534
Authors:  Chen, Shijie;  Li, Linjuan;  Chen, Yantao;  Hu, Junchi;  Liu, Jingqiu;  Liu, Yu-Chih;  Liu, Rongfeng;  Zhang, Yuanyuan;  Meng, Fanwang;  Zhu, Kongkai;  Lu, Junyan;  Zheng, Mingyue;  Chen, Kaixian;  Zhang, Jin;  Jiang, Hualiang;  Yao, Zhiyi;  Luo, Cheng
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