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Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 193
Authors:  Sun, Ning;  Ren, Chaowei;  Kong, Ying;  Zhong, Hui;  Chen, Jinju;  Li, Yan;  Zhang, Jianshui;  Zhou, Yuedong;  Qiu, Xing;  Lin, Haifan;  Song, Xiaoling;  Yang, Xiaobao;  Jiang, Biao
Favorite  |  View/Download:18/0  |  Submit date:2020/04/23
Bis(vinylsulfonyl)piperazines as efficient linkers for highly homogeneous antibody-drug conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190
Authors:  Huang, Rong;  Sheng, Yao;  Wei, Ding;  Yu, Jianghui;  Chen, Hongli;  Jiang, Biao
Adobe PDF(1552Kb)  |  Favorite  |  View/Download:24/1  |  Submit date:2020/04/12
Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides 期刊论文
GENOME BIOLOGY, 2020, 卷号: 21, 期号: 1
Authors:  Cui, Yan-ru;  Wang, Shao-jie;  Chen, Jun;  Li, Jie;  Chen, Wenzhang;  Wang, Shuyue;  Meng, Bing;  Zhu, Wei;  Zhang, Zhuhong;  Yang, Bei;  Jiang, Biao;  Yang, Guang;  Ma, Peixiang;  Liu, Jia
Favorite  |  View/Download:14/0  |  Submit date:2020/03/28
A facile method for the synthesis of free-standing pillar[5]arene-based two-dimensional covalent organic monolayers in solution 期刊论文
SUPRAMOLECULAR CHEMISTRY, 2020
Authors:  Qiang, Hui;  Hu, Wei-Bo;  Chen, Tao;  Liu, Yahu A.;  Jia, Xue-Shun;  Jiang, Biao;  Wen, Ke
Favorite  |  View/Download:20/0  |  Submit date:2020/01/17
Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 20, 页码: 9281-9298
Authors:  Zhao, Quanju;  Ren, Chaowei;  Liu, Linyi;  Chen, Jinju;  Shao, Yubao;  Sun, Ning;  Sun, Renhong;  Kong, Ying;  Ding, Xinyu;  Zhang, Xianfang;  Xu, Youwei;  Yang, Bei;  Yin, Qianqian;  Yang, Xiaobao;  Jiang, Biao
View  |  Adobe PDF(1103Kb)  |  Favorite  |  View/Download:76/32  |  Submit date:2019/11/06
一种靶向于EGFR的抗体-药物偶联物及其制备方法与应用 专利
专利类型: 发明专利, 公开日期: 2019-09-24
Inventors:  姜标;  陈红莉;  黄容;  盛耀
View  |  Adobe PDF(1660Kb)  |  Favorite  |  View/Download:52/9  |  Submit date:2019/12/26
A novel mass spectrometry-cleavable, phosphate-based enrichable and multi-targeting protein cross-linker 期刊论文
CHEMICAL SCIENCE, 2019, 卷号: 10, 期号: 26, 页码: 6443-6447
Authors:  Huang, Rong;  Zhu, Wei;  Wu, Yue;  Chen, Jiakang;  Yu, Jianghui;  Jiang, Biao;  Chen, Hongli;  Chen, Wenzhang
Adobe PDF(1074Kb)  |  Favorite  |  View/Download:50/2  |  Submit date:2019/07/26
一种哌嗪类二乙烯基磺酰胺类链接子及其制备方法与应用 专利
专利类型: 发明专利, 公开日期: 2019-09-20
Inventors:  姜标;  陈红莉;  黄容;  盛耀;  赵存良
View  |  Adobe PDF(1390Kb)  |  Favorite  |  View/Download:23/6  |  Submit date:2019/12/26
Photoactivatable Fluorogenic Labeling via Turn-On "Click-Like" Nitroso-Diene Bioorthogonal Reaction 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 13
Authors:  Li, Bai;  Zhou, Xian-Hao;  Yang, Peng-Yu;  Zhu, Liping;  Zhong, Yuan;  Cai, Zhengjun;  Jiang, Biao;  Cai, Xiaoqing;  Liu, Jia;  Jiang, Xianxing
Adobe PDF(5675Kb)  |  Favorite  |  View/Download:38/0  |  Submit date:2019/08/20
H2O-Regulated Chemoselectivity in Oxa- Versus Aza-Michael Reactions 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 11, 页码: 4159-4162
Authors:  Huang, Rong;  Li, Zhihong;  Yu, Jianghui;  Chen, Hongli;  Jiang, Biao
Adobe PDF(2011Kb)  |  Favorite  |  View/Download:56/4  |  Submit date:2019/07/01