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A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
Authors:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye;  Cao, Haijie;  Huang, Xi-Ping;  Cai, Xiaoqing;  Sun, Wen;  Ye, Na;  Xu, Yueming;  Peng, Yao;  Zhao, Suwen;  Liu, Zhi-Jie;  Zhong, Guisheng;  Wang, Ming-Wei;  Shui, Wenqing
Favorite  |  View/Download:1/0  |  Submit date:2020/03/28
Common activation mechanism of class A GPCRs 期刊论文
ELIFE, 2019, 卷号: 8
Authors:  Zhou, Qingtong;  Yang, Dehua;  Wu, Meng;  Guo, Yu;  Guo, Wangjing;  Zhong, Li;  Cai, Xiaoqing;  Dai, Antao;  Jang, Wonjo;  Shakhnovich, Eugene I.;  Liu, Zhi-Jie;  Stevens, Raymond C.;  Lambert, Nevin A.;  Babu, M. Madan;  Wang, Ming-Wei;  Zhao, Suwen
Favorite  |  View/Download:15/0  |  Submit date:2020/02/21
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
Authors:  Wan, Fangping;  Zhu, Yue;  Hu, Hailin;  Dai, Antao;  Cai, Xiaoqing;  Chen, Ligong;  Gong, Haipeng;  Xia, Tian;  Yang, Dehua;  Wang, Ming-Wei;  Zeng, Jianyang
Favorite  |  View/Download:0/0  |  Submit date:2020/03/27
Photoactivatable Fluorogenic Labeling via Turn-On "Click-Like" Nitroso-Diene Bioorthogonal Reaction 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 13
Authors:  Li, Bai;  Zhou, Xian-Hao;  Yang, Peng-Yu;  Zhu, Liping;  Zhong, Yuan;  Cai, Zhengjun;  Jiang, Biao;  Cai, Xiaoqing;  Liu, Jia;  Jiang, Xianxing
Adobe PDF(5675Kb)  |  Favorite  |  View/Download:35/0  |  Submit date:2019/08/20
Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor 期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 13, 页码: 8162-8169
Authors:  Lu, Yan;  Qin, Shanshan;  Zhang, Bingjie;  Dai, Antao;  Cai, Xiaoqing;  Ma, Mengna;  Gao, Zhan-Guo;  Yang, Dehua;  Stevens, Raymond C.;  Jacobson, Kenneth A.;  Wang, Ming-Wei;  Shui, Wenqing
Adobe PDF(3330Kb)  |  Favorite  |  View/Download:68/3  |  Submit date:2019/08/20
Programmable Vanishing Multifunctional Optics 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 4
Authors:  Cai, Xiaoqing;  Zhou, Zhitao;  Tao, Tiger H.
Adobe PDF(2083Kb)  |  Favorite  |  View/Download:59/0  |  Submit date:2019/03/12
High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening 期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 12, 页码: 3192-3199
Authors:  Qin, Shanshan;  Meng, Mengmeng;  Yang, Dehua;  Bai, Wenwen;  Lu, Yan;  Peng, Yao;  Song, Gaojie;  Wu, Yiran;  Zhou, Qingtong;  Zhao, Suwen;  Huang, Xiping;  McCorvy, John D.;  Cai, Xiaoqing;  Dai, Antao;  Roth, Bryan L.;  Hanson, Michael A.;  Liu, Zhi-Jie;  Wang, Ming-Wei;  Stevens, Raymond C.;  Shui, Wenqing
Adobe PDF(809Kb)  |  Favorite  |  View/Download:172/26  |  Submit date:2018/04/11
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist 期刊论文
CELL DISCOVERY, 2018, 卷号: 4
Authors:  Yin, Wanchao;  Zhou, X. Edward;  Yang, Dehua;  de Waal, Parker W.;  Wang, Meitian;  Dai, Antao;  Cai, Xiaoqing;  Huang, Chia-Ying;  Liu, Ping;  Wang, Xiaoxi;  Yin, Yanting;  Liu, Bo;  Zhou, Yu;  Wang, Jiang;  Liu, Hong;  Caffrey, Martin;  Melcher, Karsten;  Xu, Yechun;  Wang, Ming-Wei;  Xu, H. Eric;  Jiang, Yi
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Structure of the glucagon receptor in complex with a glucagon analogue 期刊论文
NATURE, 2018, 卷号: 553, 期号: 7686, 页码: 106-+
Authors:  Zhang, Haonan;  Qiao, Anna;  Yang, Linlin;  Van Eps, Ned;  Frederiksen, Klaus S.;  Yang, Dehua;  Dai, Antao;  Cai, Xiaoqing;  Zhang, Hui;  Yi, Cuiying;  Cao, Can;  He, Lingli;  Yang, Huaiyu;  Lau, Jesper;  Ernst, Oliver P.;  Hanson, Michael A.;  Stevens, Raymond C.;  Wang, Ming-Wei;  Reedtz-Runge, Steffen;  Jiang, Hualiang;  Zhao, Qiang;  Wu, Beili
Adobe PDF(5750Kb)  |  Favorite  |  View/Download:138/2  |  Submit date:2018/03/01
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators 期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
Authors:  Song, Gaojie;  Yang, Dehua;  Wang, Yuxia;  de Graaf, Chris;  Zhou, Qingtong;  Jiang, Shanshan;  Liu, Kaiwen;  Cai, Xiaoqing;  Dai, Antao;  Lin, Guangyao;  Liu, Dongsheng;  Wu, Fan;  Wu, Yiran;  Zhao, Suwen;  Ye, Li;  Han, Gye Won;  Lau, Jesper;  Wu, Beili;  Hanson, Michael A.;  Liu, Zhi-Jie;  Wang, Ming-Wei;  Stevens, Raymond C.
Adobe PDF(5935Kb)  |  Favorite  |  View/Download:248/1  |  Submit date:2017/07/04