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Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
Authors:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo;  Li, Chunpu;  Liu, Qiufeng;  Zhou, Yuanyang;  Wang, Bao;  Zhu, Mingrui;  Cui, Rongrong;  Tan, Xiaoqin;  Xiong, Zhaoping;  Liu, Jia;  Tan, Minjia;  Xu, Yechun;  Geng, Meiyu;  Jiang, Hualiang;  Liu, Hong;  Ai, Jing;  Zheng, Mingyue
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Artificial intelligence in drug design 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204
Authors:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun;  Xiong, Zhaoping;  Lu, Dong;  Wu, Xiaolong;  Zhao, Jihui;  Tan, Xiaoqin;  Li, Fei;  Luo, Xiaomin;  Li, Zhaojun;  Chen, Kaixian;  Zheng, Mingyue;  Jiang, Hualiang
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Computational chemical biology and drug design: Facilitating protein structure, function, and modulation studies 期刊论文
MEDICINAL RESEARCH REVIEWS, 2018, 卷号: 38, 期号: 3, 页码: 914-950
Authors:  Zheng, Mingyue;  Zhao, Jihui;  Cui, Chen;  Fu, Zunyun;  Li, Xutong;  Liu, Xiaohong;  Ding, Xiaoyu;  Tan, Xiaoqin;  Li, Fei;  Luo, Xiaomin;  Chen, Kaixian;  Jiang, Hualiang
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Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOTI L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-L-methionine (SAM)-Dependent Methyltransferase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 2026-2036
Authors:  Wang, Yulan;  Li, Linjuan;  Zhang, Bidong;  Xing, Jing;  Chen, Shijie;  Wan, Wei;  Song, Yakai;  Jiang, Hao;  Jiang, Hualiang;  Luo, Cheng;  Zheng, Mingyue
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Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534
Authors:  Chen, Shijie;  Li, Linjuan;  Chen, Yantao;  Hu, Junchi;  Liu, Jingqiu;  Liu, Yu-Chih;  Liu, Rongfeng;  Zhang, Yuanyuan;  Meng, Fanwang;  Zhu, Kongkai;  Lu, Junyan;  Zheng, Mingyue;  Chen, Kaixian;  Zhang, Jin;  Jiang, Hualiang;  Yao, Zhiyi;  Luo, Cheng
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Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 20, 页码: 8166-8181
Authors:  Meng, Fanwang;  Cheng, Sufang;  Ding, Hong;  Liu, Shien;  Liu, Yan;  Zhu, Kongkai;  Chen, Shijie;  Lu, Junyan;  Xie, Yiqian;  Li, Linjuan;  Liu, Rongfeng;  Shi, Zhe;  Zhou, Yu;  Liu, Yu-Chih;  Zheng, Mingyue;  Jiang, Hualiang;  Lu, Wencong;  Liu, Hong;  Luo, Cheng
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Identifying Novel Selective Non-Nucleoside DNA Methyltransferase 1 Inhibitors through Docking-Based Virtual Screening 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 21, 页码: 9028-9041
Authors:  Chen, Shijie;  Wang, Yulan;  Zhou, Wen;  Li, Shanshan;  Peng, Jianlong;  Shi, Zhe;  Hu, Junchi;  Liu, Yu-Chih;  Ding, Hong;  Lin, Yijyun;  Li, Linjuan;  Cheng, Sufang;  Liu, Jingqiu;  Lu, Tao;  Jiang, Hualiang;  Liu, Bo;  Zheng, Mingyue;  Luo, Cheng
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In Silico target fishing: addressing a "Big Data" problem by ligand-based similarity rankings with data fusion 期刊论文
JOURNAL OF CHEMINFORMATICS, 2014, 卷号: 6
Authors:  Liu, Xian;  Xu, Yuan;  Li, Shanshan;  Wang, Yulan;  Peng, Jianlong;  Luo, Cheng;  Luo, Xiaomin;  Zheng, Mingyue;  Chen, Kaixian;  Jiang, Hualiang
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Mechanism of the All-alpha to All-beta Conformational Transition of RfaH-CTD: Molecular Dynamics Simulation and Markov State Model 期刊论文
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2014, 卷号: 10, 期号: 6, 页码: 2255-2264
Authors:  Li, Shanshan;  Xiong, Bing;  Xu, Yuan;  Lu, Tao;  Luo, Xiaomin;  Luo, Cheng;  Shen, Jingkang;  Chen, Kaixian;  Zheng, Mingyue;  Jiang, Hualiang
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