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Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
Authors:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang;  Zhang, Tao;  Xie, Hua;  Li, Hong-lin;  Ding, Jian
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Mutual inhibitions between epidermal growth factor receptor signaling and miR-124a control pancreatic progenitor proliferation 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 8, 页码: 12978-12988
Authors:  Zhang, Zhenwu;  Zhai, Wenjun;  Liang, Jie;  Chen, Zhenbao;  Ma, Mingjun;  Zhao, Yicheng;  Liang, Yang;  Li, Xuyan;  Teng, Chun-Bo
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Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
Authors:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang;  Hao, Yongjia;  Dou, Dou;  Liu, Yingqiang;  Ding, Jian;  Zhao, Zhenjiang;  Xie, Hua;  Li, Honglin
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Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator 期刊论文
CELLS, 2019, 卷号: 8, 期号: 8
Authors:  Lu, Yi;  Dai, Jing;  Kong, Na;  Liu, Jianghuai;  Gong, Jinkang;  Yao, Yuan
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Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
Authors:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting;  Wang, Peipei;  Hu, Xiaobei;  Fang, Sui;  Gao, Anhui;  Zhou, Yubo;  Liu, Tao;  Li, Jia;  Hu, Yongzhou
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CHML promotes liver cancer metastasis by facilitating Rab14 recycle 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10
Authors:  Chen, Tian-Wei;  Yin, Fen-Fen;  Yuan, Yan-Mei;  Guan, Dong-Xian;  Zhang, Erbin;  Zhang, Feng-Kun;  Jiang, Hao;  Ma, Ning;  Wang, Jing-Jing;  Ni, Qian-Zhi;  Qiu, Lin;  Feng, Jing;  Zhang, Xue-Li;  Bao, Ying;  Wang, Kang;  Cheng, Shu-Qun;  Wang, Xiao-Fan;  Wang, Xiang;  Li, Jing-Jing;  Xie, Dong
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XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10
Authors:  Zhu, Zhi-Chuan;  Liu, Ji-Wei;  Yang, Can;  Zhao, Miao;  Xiong, Zhi-Qi
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Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells 期刊论文
HUMAN GENE THERAPY, 2019, 卷号: 30, 期号: 4, 页码: 446-458
Authors:  Hu, Bian;  Zou, Yan;  Zhang, Linlin;  Tang, Jiaxing;  Niedermann, Gabriele;  Firat, Elke;  Huang, Xingxu;  Zhu, Xuekai
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Novel Triapine Derivative Induces Copper-Dependent Cell Death in Hematopoietic Cancers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3107-3121
Authors:  Chen, Ge;  Niu, Chunyi;  Yi, Jianhua;  Sun, Lin;  Cao, Hengyi;  Fang, Yanjia;  Jin, Taijie;  Li, Ying;  Lou, Chunli;  Kang, Jingwu;  Wei, Wanguo;  Zhu, Jidong
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Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9
Authors:  Gao, Longfei;  Huang, Shichao;  Zhang, Hong;  Hua, Wei;  Xin, Shunmei;  Cheng, Lin;  Guan, Wuqiang;  Yu, Yongchun;  Mao, Ying;  Pei, Gang
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