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Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289
作者:  Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen
Adobe PDF(2887Kb)  |  收藏  |  浏览/下载:43/1  |  提交时间:2025/03/25
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文
MOLECULAR DIVERSITY, 2025
作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue
Adobe PDF(4175Kb)  |  收藏  |  浏览/下载:71/2  |  提交时间:2025/03/03
Design, Synthesis and Biological Activity Study of γ-Aminobutyric Acid (GABA) Derivatives Containing Bridged Bicyclic Skeletons as BCAT1 Inhibitors 期刊论文
MOLECULES, 2025, 卷号: 30, 期号: 4
作者:  Luo, Wen;  Pan, Zilu;  Zhu, Xinyuan;  Li, Yan;  Li, Yong
Adobe PDF(2448Kb)  |  收藏  |  浏览/下载:51/1  |  提交时间:2025/03/10
Synthesis and Biological Evaluation of β‐Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2024
作者:  Chenmao Zhou;  Xinyue Hao;  Zhengyang Chen;  Runze Zhang;  Qian Zhou
Adobe PDF(3478Kb)  |  收藏  |  浏览/下载:138/0  |  提交时间:2024/11/27
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 130
作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin
Adobe PDF(8940Kb)  |  收藏  |  浏览/下载:389/0  |  提交时间:2022/12/02
Direct synthesis of higher oxygenates via syngas over zinc oxide modified CoMn-based catalysts 期刊论文
APPLIED CATALYSIS A: GENERAL, 2022, 卷号: 648
作者:  Qi, Xingzhen;  Lin, Tiejun;  Gong, Kun;  Wang, Xinxing;  Lv, Dong
Adobe PDF(8561Kb)  |  收藏  |  浏览/下载:266/0  |  提交时间:2022/11/18
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110
作者:  Lin, Lin;  Lin, Guangyao;  Zhou, Qingtong;  Bathgate, Ross A. D.;  Gong, Grace Qun
Adobe PDF(4286Kb)  |  收藏  |  浏览/下载:236/0  |  提交时间:2021/07/23
Progress in Biological Activity and Synthesis of Nematode Hatching Pheromone Glycinoeclepin A 期刊论文
有机化学, 2021, 卷号: 41, 期号: 2, 页码: 553-566
作者:  Ma Ding;  Ao Junli;  Hu Naifeng;  Liang Guangxin
Adobe PDF(869Kb)  |  收藏  |  浏览/下载:258/2  |  提交时间:2021/05/28
Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 期号: 115871, 页码: 1-12
作者:  Hao, Guiyun;  Li, Hao;  Yang, Fei;  Dong, Duoling;  Li, Zezhong
Adobe PDF(2529Kb)  |  收藏  |  浏览/下载:348/0  |  提交时间:2021/04/01
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang
Adobe PDF(2955Kb)  |  收藏  |  浏览/下载:485/9  |  提交时间:2019/08/20
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