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Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia 期刊论文
ACTA PHARMACOLOGICA SINICA, 2025
作者:  Chen, Yu-jun;  Zhao, Yu;  Yao, Ming-yue;  Wang, Ya-fang;  Ma, Ming
Adobe PDF(6202Kb)  |  收藏  |  浏览/下载：99/7  |  提交时间：2025/02/12
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 124
作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu
Adobe PDF(2004Kb)  |  收藏  |  浏览/下载：183/0  |  提交时间：2022/05/05
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
Adobe PDF(5109Kb)  |  收藏  |  浏览/下载：392/1  |  提交时间：2021/05/14
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52
作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：341/0  |  提交时间：2022/04/12
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:  Lu, Wenchao;  Xiong, Huan;  Chen, Yu;  Wang, Chen;  Zhang, Hao
Adobe PDF(5322Kb)  |  收藏  |  浏览/下载：522/0  |  提交时间：2018/12/10
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