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TNFR2/CCR8 bispecific antibody enhances antitumor activity through depleting Ti-Tregs and boosting effector CD8
+
T cell function
期刊论文
ONCOIMMUNOLOGY, 2025, 卷号: 14, 期号: 1
作者:
Wang, Ran
;
Xu, Jiefang
;
Cheng, Shipeng
;
Ling, Zhiyang
;
Sonam, Wangmo
Adobe PDF(5792Kb)
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收藏
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浏览/下载:23/3
|
提交时间:2025/05/12
FT10-Fab
TNFR2
CCR8
Ti-Tregs
CD8(+) T cell
antitumour
immunotherapy
Multipath Synergistic Immune Activation of Hydrogels Delivering STING Agonist and siXkr8 for Long-Lasting Colorectal Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2025
作者:
Yang, Ning
;
Feng, Xiaolong
;
Yin, Lixuan
;
Bi, Hongjie
;
Fu, Zirang
Adobe PDF(13373Kb)
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收藏
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浏览/下载:9/3
|
提交时间:2025/06/04
colorectal cancer
cyclic diguanosine
hydrogel
immunotherapy
siRNA
Evaluation of tumorous LCP1 and ADPGK as predictive biomarker for immune-related adverse events in bone and soft tissue sarcomas treated with anti-PD-1 and anti-PD-L1 antibodies
期刊论文
BMC CANCER, 2025, 卷号: 25, 期号: 1
作者:
Zhang, Qing
Adobe PDF(1838Kb)
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收藏
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浏览/下载:35/1
|
提交时间:2025/04/14
Immunotherapy
irAE
Sarcoma
Biomarker
ICI
A myeloid IFN gamma response gene signature correlates with cancer prognosis
期刊论文
CLINICAL AND TRANSLATIONAL MEDICINE, 2025, 卷号: 15, 期号: 4
作者:
Zhang, Yuchao
;
Khanniche, Asma
;
Li, Yizhe
;
Wu, Zhenchuan
;
Wang, Hailong
Adobe PDF(7661Kb)
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收藏
|
浏览/下载:26/2
|
提交时间:2025/04/14
anti-PD1 immunotherapy
IFN-gamma response genes
LASSO
pan-cancer
prognosis
tumour microenvironment
Tumor Microenvironment-Responsive Nano-Immunomodulators for Enhancing Chimeric Antigen Receptor-T Cell Therapy in Lung Cancer
期刊论文
ACS NANO, 2025, 卷号: 19, 期号: 8, 页码: 8212-8226
作者:
Chen, Qian
;
Sun, Jie
;
Ling, Sisi
;
Yang, Hongchao
;
Li, Tuanwei
Adobe PDF(5371Kb)
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收藏
|
浏览/下载:71/1
|
提交时间:2025/03/10
immunotherapy
CAR-T cells
NIR-II fluorescenceimaging
lung cancer
tumor microenvironment
Interleukin 15-Presenting Nanovesicles with Doxorubicin-Loaded Ferritin Cores for Cancer Immunochemotherapy
期刊论文
ADVANCED SCIENCE, 2025, 卷号: 12, 期号: 4
作者:
Zhai, Yihui
;
Zhang, Wen
;
Wang, Jinming
;
Kong, Ying
;
Rong, Rong
Adobe PDF(5190Kb)
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收藏
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浏览/下载:177/3
|
提交时间:2024/12/17
CTLs
IL15, immunotherapy
nanovesicles
NK cells
Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy
期刊论文
CANCER MEDICINE, 2025, 卷号: 14, 期号: 1
作者:
Wang, Kun
;
Zhang, Yingying
;
Su, Zhaoming
;
Wang, Bei
;
Zhou, Yuanyang
Adobe PDF(6595Kb)
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收藏
|
浏览/下载:140/1
|
提交时间:2025/01/20
biomarker
CDC42
clinical response
immunotherapy
pan-cancer
Closed-Loop Control of Macrophage Engineering Enabled by Focused-Ultrasound Responsive Mechanoluminescence Nanoplatform for Precise Cancer Immunotherapy
期刊论文
SMALL, 2024, 卷号: 20, 期号: 46
作者:
Xu, Sixin
;
Meng, Lingkai
;
Hu, Qian
;
Li, Fang
;
Zhang, Jieying
Adobe PDF(11276Kb)
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收藏
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浏览/下载:254/10
|
提交时间:2024/08/23
Chemical activation
Diseases
Feedback
Infrared devices
Macrophages
Tumors
Ultrasonics
Bio-imaging
Cancer immunotherapy
Cancer therapy
Closed-loop control
Focused ultrasound
Immunomodulators
Macrophage engineering
Mechanoluminescence nanomaterial
Optical-
Spatiotemporal control
Enhancing immunotherapy efficacy against MHC-I deficient triple-negative breast cancer using LCL161-loaded macrophage membrane-decorated nanoparticles
期刊论文
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3218-3231
作者:
Zhang, Wen
;
Zhai, Yihui
;
Cai, Ying
;
Gong, Xiang
;
Jiang, Yunxuan
Adobe PDF(3490Kb)
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收藏
|
浏览/下载:277/2
|
提交时间:2024/07/22
MHC-I deficiency
Macrophage
CD47
Immunotherapy
Triple-negative breast cancer
Phagocytosis
Immune checkpoint
Innate immunity
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
ADVANCED MATERIALS, 2024, 卷号: 36, 期号: 3
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
Adobe PDF(5155Kb)
|
收藏
|
浏览/下载:303/2
|
提交时间:2023/12/22
Cell death
Diseases
Endothelial cells
Ligands
Peptides
T-cells
Drug-conjugates
Endothelial-cells
Fas ligand
Immunotherapy
Integrin targeting
Peptide drugs
Peptide-drug conjugate
T lymphocytes
Triple-negative breast cancers
Tumor-associated endothelial cell
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