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Visualization of membrane localization and the functional state of CB2R pools using matched agonist and inverse agonist probe pairs 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 44, 页码: 18443-18454
作者:  Wasinska-Kalwa, M.;  Omran, A.;  Mach, L.;  Scipioni, L.;  Bouma, J.
Adobe PDF(1029Kb)  |  收藏  |  浏览/下载：252/3  |  提交时间：2024/10/28
Structural basis for activation of somatostatin receptor 5 by cyclic neuropeptide agonists 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 26
作者:  Li, Jingru;  You, Chongzhao;  Li, Yang;  Li, Changyao;  Fan, Wenjia
Adobe PDF(9327Kb)  |  收藏  |  浏览/下载：245/4  |  提交时间：2024/07/08
Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 20, 页码: 14011–14028
作者:  Jianhang Mao;  Yilong Cui;  Huan Wang;  Wenwen Duan;  Zhi-Jie Liu
Adobe PDF(3407Kb)  |  收藏  |  浏览/下载：920/307  |  提交时间：2023/12/01
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists 期刊论文
ACS CENTRAL SCIENCE, 2023, 卷号: 10, 期号: 5, 页码: 956-968
作者:  Kosar, Miroslav;  Sarott, Roman C.;  Sykes, David A.;  Viray, Alexander E. G.
Adobe PDF(8180Kb)  |  收藏  |  浏览/下载：257/0  |  提交时间：2024/04/12
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241
作者:  Shen, Ancheng;  Li, Xiyuan;  Zhang, Yan;  Ma, Jing;  Xiao, Ruoxuan
Adobe PDF(6740Kb)  |  收藏  |  浏览/下载：417/0  |  提交时间：2023/01/16
Crystal structure of a constitutive active mutant of adenosine A(2A) receptor 期刊论文
IUCRJ, 2022, 卷号: 9
作者:  Cui, Min;  Zhou, Qingtong;  Xu, Yueming;  Weng, Yuan;  Yao, Deqiang
Adobe PDF(1345Kb)  |  收藏  |  浏览/下载：2270/632  |  提交时间：2022/05/31
GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Chen, Yan;  Xu, Ying-na;  Ye, Chen-yu;  Feng, Wen-bo;  Zhou, Qing-tong
Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：359/0  |  提交时间：2022/01/04
Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo 期刊论文
ADVANCED SCIENCE, 2020
作者:  Tao, Pingdong;  Kuang, Yuanyuan;  Li, Yu;  Li, Wenping;  Gao, Zibei
Adobe PDF(4012Kb)  |  收藏  |  浏览/下载：562/8  |  提交时间：2020/07/20
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