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Deuterium substitution at the intolerable site as a strategy to mitigate the toxicity of camptothecin derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296
作者:
Yu, Xianqiang
;
Sun, Ziyu
;
Liu, Jing
;
Huangfu, Shangwei
;
Cheng, Qi
Adobe PDF(11608Kb)
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浏览/下载:15/4
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提交时间:2025/07/07
Camptothecin
Deuterium substitution
Toxicity
In vivo efficacy
Critical current density and AC magnetic susceptibility of high-quality FeTe0.5Se0.5 superconducting tapes
期刊论文
SUPERCONDUCTIVITY, 2024, 卷号: 12
作者:
Zhou, Xin
;
Li, Wenjie
;
Hou, Qiang
;
Wei, Wei
;
Liu, Wenhui
Adobe PDF(1377Kb)
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收藏
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浏览/下载:297/1
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提交时间:2024/11/08
Critical current density (superconductivity)
Electric tapes
Flux pinning
Iron-based Superconductors
Magnetooptical effects
Optical image storage
Optical tomography
Organic superconducting materials
Pulsed laser deposition
Reels
Threshold current density
'current
AC Magnetic susceptibility
Coated conductors
Fese0.5te0.5
High magnetic fields
High quality
Magnetic susceptibility measurements
Magnetooptical imaging
Non-toxicity
Simple structures
Astrocyte-specific secretome profiling reveals its correlation with neurological disorders
预印本
2024
作者:
Liu, Jie
;
Gao, Jing
;
Guo, Lin
;
Ma, Guoming
Adobe PDF(7310Kb)
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浏览/下载:269/63
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提交时间:2025/01/06
Astrocyte
Secretome
Click chemistry
Neurological disorders
non-cell autonomous toxicity
Chemical conjugation mitigates immunotoxicity of chemotherapy via reducing receptor-mediated drug leakage from lipid nanoparticles
期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 23
作者:
Zheng, Chao
;
Zhang, Wen
;
Gong, Xiang
;
Xiong, Fengqin
;
Jiang, Linyang
Adobe PDF(7471Kb)
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浏览/下载:343/7
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提交时间:2024/06/21
Diseases
Drug delivery
Lipoproteins
Liposomes
Mammals
Medical nanotechnology
Tumors
Cancer therapy
Drug leakage
High density lipoprotein
Immunotoxicity
Lipid nanoparticles
Low toxicity
Lymph node
Maytansine
Nanocarriers
Optimal design
Ligand Engineering in Tin-Based Perovskite Solar Cells
期刊论文
NANO-MICRO LETTERS, 2023, 卷号: 15, 期号: 1
作者:
Li, Peizhou
;
Cao, Xiangrong
;
Li, Jingrui
;
Jiao, Bo
;
Hou, Xun
Adobe PDF(3780Kb)
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浏览/下载:1333/241
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提交时间:2023/07/21
Carrier lifetime
Carrier mobility
Cell engineering
Conversion efficiency
Crystal orientation
Defect engineering
Ligands
Perovskite solar cells
Solar power generation
Tin compounds
Toxicity
Band-gap structures
Commercialisation
Film fabrication
Large-scale applications
Lead-Free
Lead-free perovskites
Ligand engineering
Low toxicity
Photovoltaics
Power conversion efficiencies
Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth
期刊论文
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964
作者:
Ding, Chunyong
;
Du, Mengyan
;
Xiong, Zhi
;
Wang, Xue
;
Li, Hongji
Adobe PDF(1667Kb)
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浏览/下载:347/1
|
提交时间:2023/06/02
Carbonic anhydrase
Cell growth
Cell signaling
Chemical activation
Growth kinetics
Toxicity
Tumors
Adapter proteins
Blue light
Cell targeting
Clinical development
Critical challenges
Innate immunes
Synthesised
Tumour cells
Up-regulation
Zebrafish embryos
Synergic Electron and Defect Compensation Minimizes Voltage Loss in Lead-Free Perovskite Solar Cells
期刊论文
ANGEWANDTE CHEMIE - INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 39
作者:
Liu, Gengling
;
Jiang, Xianyuan
;
Feng, Wenhuai
;
Yang, Guo
;
Chen, Xi
Adobe PDF(1504Kb)
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浏览/下载:471/1
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提交时间:2023/07/28
Defects
Electric losses
Electronic structure
Metal halides
Perovskite solar cells
Semiconductor doping
Tin
Carrier dynamics
Defect compensation
Electric doping
Lead-free perovskites
Low toxicity
Optoelectronics property
P-doping
P-type
Vacancy Defects
Voltage loss
Determining the Dose-Response Curve of Exoelectrogens: A Microscale Microbial Fuel Cell Biosensor for Water Toxicity Monitoring
期刊论文
MICROMACHINES, 2022, 卷号: 13, 期号: 10
作者:
Fei, Sitao
;
Ren, Hao
Adobe PDF(1616Kb)
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浏览/下载:1393/727
|
提交时间:2022/11/08
microbial fuel cell (MFC)
biosensor
dose-response curve
water toxicity monitoring
exoelectrogen
A novel copper-sensing two-component system for inducing Dsb gene expression in bacteria
期刊论文
SCIENCE BULLETIN, 2022, 卷号: 67, 期号: 2
作者:
Yu, Liang
;
Cao, Qiao
;
Chen, Weizhong
;
Yang, Nana
;
Yang, Cai-Guang
Adobe PDF(5408Kb)
|
收藏
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浏览/下载:561/260
|
提交时间:2021/12/17
Amino acids
Copper
Covalent bonds
Metal ions
Phosphatases
Sulfur compounds
Transcription
Copper resistance
Copper toxicity
Disulfide bond formation
Gene-regulation
Genes expression
Histidine kinase
Human pathogens
Pseudomonas aeruginosa
Response regulators
Two component systems
Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study of Pt(6)GS(4)
期刊论文
SMALL, 2020, 卷号: 16, 期号: 26
作者:
Zhang, Chunyu
;
Gao, Liang
;
Yuan, Qing
;
Zhao, Lina
;
Niu, Wenchao
Adobe PDF(2557Kb)
|
收藏
|
浏览/下载:1020/0
|
提交时间:2020/06/19
anti-cancer treatment
GSH-Pt adducts
non-toxicity
Pt drug inactivation
Pt(6)GS(4)
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