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High-Efficiency Ocular Delivery of Brain-Derived Neurotrophic Factor and Oligomycin for Neuroprotection in Glaucoma
期刊论文
ADVANCED MATERIALS, 2025
作者:
Adobe PDF(12288Kb)
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浏览/下载:32/8
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提交时间:2025/05/13
gene therapy
M & uuml
glaucoma
ller cell
neuroprotection
retinal ganglion cell
Deciphering enhancers of hearing loss genes for efficient and targeted gene therapy of hereditary deafness
期刊论文
NEURON, 2025
作者:
Simeng Zhao
;
Qiuxiang Yang
;
Zehua Yu
;
Cenfeng Chu
;
Shengqi Dai
Adobe PDF(9318Kb)
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收藏
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浏览/下载:49/8
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提交时间:2025/05/12
hereditary hearing loss
gene therapy
adeno-associated viruses
AAVs
outer hair cell
OHC
Slc26a5
transcriptional enhancer
conserved non-coding elements
CNEs
Engineered bacterium-nanomedicine complexes in cancer therapy: Designs, applications and challenges
期刊论文
NANO TODAY, 2025, 卷号: 61
作者:
Jie, Zhongming
;
Yan, Xiaoli
;
Xiong, Bingyan
;
Shi, Jianlin
Adobe PDF(32760Kb)
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浏览/下载:157/3
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提交时间:2025/01/10
Nanoclay
Cancer therapy
Complex
Design applications
Design challenges
Engineered bacteria
Secretion
Side effect
Therapy design
Tumor penetration
Tumor therapy
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
MOLECULAR DIVERSITY, 2025
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
Adobe PDF(4175Kb)
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浏览/下载:76/2
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提交时间:2025/03/03
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Neutron Activation Dose Assessment Based on a Human Head Phantom Post-BNCT
期刊论文
HEALTH PHYSICS, 2025
作者:
Wu GC(吴灌潮)
;
Lin ZK(林作康)
;
Zhang ZJ(张子健)
;
Lin ZY(林志远)
;
Zhu YN(朱益楠)
Adobe PDF(664Kb)
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收藏
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浏览/下载:41/3
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提交时间:2025/04/14
Dose assessment
Internal dose
Radiation protection
Radiation therapy
A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
Adobe PDF(18107Kb)
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浏览/下载:87/2
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提交时间:2025/02/12
Ablation
Biological organs
Chemotherapy
Gene expression
Gene therapy
Lung cancer
Mammals
Nanoparticles
Oligonucleotides
Transplantation (surgical)
Docetaxel
Endosomal escapes
Nano-devices
PH-responsive
Prodrug nanoparticle
Prodrugs
Receptor 1 small interference RNA
Receptor-1
Small interference RNA
Triple-negative breast cancers
Rapid, Non-Invasive, Accurate Diagnosis and Efficient Clearance of Metastatic Lymph Nodes
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 卷号: 64, 期号: 5
作者:
Ling, Sisi
;
Yang, Hongchao
;
Wu, Feng
;
Yang, Xiaohu
;
Li, Tuanwei
Adobe PDF(2235Kb)
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浏览/下载:215/2
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提交时间:2024/12/17
chemical resonance energy transfer
NIR-II fluorescence
tumor metastasis
sentinel lymph node
diagnosis and therapy
Analysis of the Influence of Boron Distribution on Compound Biological Effectiveness Values in Boron Neutron Capture Therapy
期刊论文
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2025
作者:
Lin, Zhiyuan
;
Lin, Zuokang
;
Zhang, Zijian
;
Wu, Guanchao
;
Zhu, Yinan
Adobe PDF(972Kb)
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收藏
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浏览/下载:37/2
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提交时间:2025/03/28
Biological effectiveness
Boron distribution
Boron neutron capture therapy
Boron neutroncapture therapy
Cancer cells
Cell nucleus
Cellular levels
Effectiveness factor
Monte Carlo's simulation
Selectively destroy
Mild Focused Ultrasound-Induced Microscopic Heating of Nanoparticles Observed by Lanthanide Luminescence for Precise Sonothermal Cancer Therapy
期刊论文
NANO LETTERS, 2024, 卷号: 25, 期号: 1, 页码: 391-400
作者:
Meng, Lingkai
;
Xu, Sixin
;
Hu, Qian
;
Wang, Hao
;
Wang, Pengrui
Adobe PDF(9254Kb)
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浏览/下载:73/4
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提交时间:2025/01/10
Ultrasonic applications
Ultrasonic transmission
Ultrasonics
Cancer therapy
Focused ultrasound
Intensity ratio
Lanthanide luminescence
Luminescence intensity
Microscopic heating
Side effect
Temperature detection
Thermal ablation
Ultrasound transmissions
A novel AAV Vector for gene therapy of RPE-related retinal degenerative diseases via intravitreal delivery
期刊论文
MOLECULAR NEURODEGENERATION, 2024, 卷号: 19, 期号: 1
作者:
Gong, Yajun
;
Huang, Xianyu
;
Tu, Tianxiang
;
Chu, Cenfeng
;
Xian, Chunrui
Adobe PDF(1205Kb)
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收藏
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浏览/下载:280/8
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提交时间:2024/12/17
Retinal pigment epithelium (RPE)
Adeno-associated virus (AAV)
Gene therapy
Retinal degenerative diseases
Age-related macular degeneration (AMD)
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