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A general temperature-guided language model to design proteins of enhanced stability and activity
期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 48
作者:
Jiang, Fan
;
Li, Mingchen
;
Dong, Jiajun
;
Yu, Yuanxi
;
Sun, Xinyu
Adobe PDF(2257Kb)
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收藏
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浏览/下载:243/6
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提交时间:2024/12/27
Antigen-antibody reactions
Antigens
'current
Enhanced stability
Language model
Learning models
Predictive abilities
Property
Protein engineering
Protein mutants
State of the art
Temperature aware
Engineered IscB-uRNA system with improved base editing efficiency for disease correction via single AAV delivery in mice
期刊论文
CELL REPORTS, 2024, 卷号: 43, 期号: 11, 页码: 114973
作者:
guo,ruochen
;
sun,xiaozhi
;
wang,feizuo
;
han,dingyi
;
yang,qiaoxia
Adobe PDF(7204Kb)
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收藏
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浏览/下载:195/5
|
提交时间:2024/12/02
Adeno-associated virus
CP: Molecular biology
CRISPR ancestry nuclease
IscB-ωRNA system
RNA-guided nuclease
adenine base editing
cytosine base editing
gene editing therapy
protein engineering
transposon-encoded OMEGA system
tyrosinemia
Expanding the toolbox of probiotic Escherichia coli Nissle 1917 for synthetic biology
预印本
2023
作者:
Ba, Fang
;
Zhang, Yufei
;
Ji, Xiangyang
;
Liu, Wan-Qiu
;
Ling, Shengjie
Adobe PDF(2683Kb)
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收藏
|
浏览/下载:319/0
|
提交时间:2024/01/09
synthetic biology
probiotic engineering
Escherichia coli Nissle 1917
cryptic plasmid
integrase
cell-free protein synthesis
Cell-free metabolic engineering enables selective biotransformation of fatty acids to value-added chemicals
期刊论文
METABOLIC ENGINEERING COMMUNICATIONS;, 2023, 卷号: 16
作者:
Liu, Yushi
;
Liu, Wan-Qiu
;
Huang, Shuhui
;
Xu, Huiling
;
Lu, Haofan
Adobe PDF(4939Kb)
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收藏
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浏览/下载:377/0
|
提交时间:2023/03/24
Biocatalysis
Biotransformation
Cell-free metabolic engineering
Cell-free protein synthesis
Fatty acids
Regulatory Part Engineering for High-Yield Protein Synthesis in an All-Streptomyces-Based Cell-Free Expression System
期刊论文
ACS SYNTHETIC BIOLOGY, 2022, 卷号: 11, 期号: 2, 页码: 570-578
作者:
Xu, Huiling
;
Yang, Chen
;
Tian, Xintong
;
Chen, Yilin
;
Liu, Wan-Qiu
Adobe PDF(2356Kb)
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收藏
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浏览/下载:487/2
|
提交时间:2022/03/17
cell-free protein synthesis
Streptomyces
regulatory part engineering
gene expression
synthetic biology
Functional amyloid-chitin hybrid ink coupled with flexible fabrication approaches for diverse macro and micro-structures
期刊论文
MATERIALS TODAY BIO, 2022, 卷号: 13
作者:
Wei, Shicao
;
Li, Yingfeng
;
Li, Ke
;
Kang, Anqi
;
Zhang, Siyu
Adobe PDF(2918Kb)
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收藏
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浏览/下载:466/1
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提交时间:2021/12/24
Cell culture
Cell engineering
Chitin
Enzyme immobilization
Genetic engineering
Glycoproteins
Self assembly
Tissue engineering
Bio-fabrication
Broad application
Chitin binding domains
Functional amyloid
Hybrid inks
Macrostructures
Micro-structures
Molecular complexes
Precise fabrications
Protein self-assemblies
Editorial: Cell-Free Synthetic Biology
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 卷号: 9
作者:
Li, Jian
;
Kwon, Yong-Chan
;
Lu, Yuan
;
Moore, Simon J.
Adobe PDF(519Kb)
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收藏
|
浏览/下载:490/151
|
提交时间:2021/12/27
cell-free systems
synthetic biology
cell-free protein synthesis
cell-free metabolic engineering
cell-free sensors
synthetic cells
biocatalysis and biotransformation
Diatom-inspired multiscale mineralization of patterned protein-polysaccharide complex structures
期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 8
作者:
Li, Ke
;
Li, Yingfeng
;
Wang, Xinyu
;
Cui, Mengkui
;
An, Bolin
Adobe PDF(3727Kb)
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收藏
|
浏览/下载:597/2
|
提交时间:2021/09/18
biomimetic mineralization
patterned porous structure
genetic engineering
amyloid protein
artificial photosynthesis
Harnessing proteins for engineered living materials
期刊论文
CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE, 2021, 卷号: 25, 期号: 1
作者:
Xu, Lianjie
;
Wang, Xinyu
;
Sun, Fei
;
Cao, Yi
;
Zhong, Chao
Adobe PDF(7367Kb)
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收藏
|
浏览/下载:244/0
|
提交时间:2021/07/23
Engineered living materials
Protein engineering
Systems chemistry
SpyCatcher
SpyTag
Biofilms
Genetic Engineering of Filamentous Fungi for Efficient Protein Expression and Secretion
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8
作者:
Adobe PDF(1059Kb)
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收藏
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浏览/下载:1106/322
|
提交时间:2020/05/14
filamentous fungi
genetic engineering
protein secretion
expression
genome engineering
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