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Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38
作者:  Hart, Jonathan R.;  Liu, Xiao;  Pan, Chen;  Liang, Anyi;  Ueno, Lynn
Adobe PDF(2340Kb)  |  收藏  |  浏览/下载：267/1  |  提交时间：2023/08/28
BCL-2 inhibitor synergizes with PI3Kδ inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2022
作者:  Ming-Yue Yao;  Ya-Fang Wang;  Yu Zhao;  Li-Jun Ling;  Ye He
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载：327/1  |  提交时间：2022/11/07
BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 8
作者:  Yao, Ming-Yue;  Wang, Ya-Fang;  Zhao, Yu;  Ling, Li-Jun;  He, Ye
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载：178/1  |  提交时间：2022/11/22
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
Adobe PDF(2602Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2021/12/03
PI3K/Akt/mTOR signaling orchestrates the phenotypic transition and chemo-resistance of small cell lung cancer 期刊论文
JOURNAL OF GENETICS AND GENOMICS, 2021, 卷号: 48, 期号: 7, 页码: 640-651
作者:  Li, Xuefeng;  Li, Cheng;  Guo, Chenchen;  Zhao, Qiqi;  Cao, Jiayu
Adobe PDF(5689Kb)  |  收藏  |  浏览/下载：406/0  |  提交时间：2021/10/15
Pictilisib Enhances the Antitumor Effect of Doxorubicin and Prevents Tumor-Mediated Bone Destruction by Blockade of PI3K/AKT Pathway 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10, 页码: #VALUE!
作者:  Liang, Chao;  Yu, Xijiao;  Xiong, Naping;  Zhang, Zhichang;  Sun, Zhenyu
Adobe PDF(11264Kb)  |  收藏  |  浏览/下载：667/218  |  提交时间：2021/04/01
Optimization of novel benzofuro[3,2-b]pyridin-2(1H)-one derivatives as dual inhibitors of BTK and PI3K delta 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 304-316
作者:  Liu, Linyi;  Li, Xinyu;  Cheng, Yu;  Wang, Lianjian;  Yang, Huizhu
Adobe PDF(2749Kb)  |  收藏  |  浏览/下载：521/1  |  提交时间：2019/02/25
A synthetic peptide hijacks the catalytic subunit of class I PI3K to suppress the growth of cancer cells 期刊论文
CANCER LETTERS, 2017, 卷号: 405, 页码: 1-9
作者:  Guo, Weiwei;  You, Xue;  Wang, Xiao;  Wang, Lin;  Chen, Yan
Adobe PDF(3862Kb)  |  收藏  |  浏览/下载：397/2  |  提交时间：2017/11/14
PAQR3 controls autophagy by integrating AMPK signaling to enhance ATG14L-associated PI3K activity 期刊论文
EMBO JOURNAL, 2016, 卷号: 35, 期号: 5, 页码: 496-514
作者:  Xu, Da-Qian;  Wang, Zheng;  Wang, Chen-Yao;  Zhang, De-Yi;  Wan, Hui-Da
Adobe PDF(3415Kb)  |  收藏  |  浏览/下载：438/1  |  提交时间：2017/07/04
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