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BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma 期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 12
作者:  Liu, Dongdong;  Li, Zhen;  Tan, Dongxia;  An, Yang;  Chu, Liping
Adobe PDF(14405Kb)  |  收藏  |  浏览/下载：537/6  |  提交时间：2024/02/02
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8
作者:  Xu, Lei;  Xuyan, Xuyang;  Minmi, Minmin;  Wang, Zhiji;  Shee, Chao
Adobe PDF(1267Kb)  |  收藏  |  浏览/下载：379/0  |  提交时间：2023/07/24
EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 4
作者:  Chu, Liping;  Tan, Dongxia;  Zhu, Meimei;  Qu, Yuxiu;  Ma, Xin
Adobe PDF(3768Kb)  |  收藏  |  浏览/下载：618/1  |  提交时间：2023/04/07
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
Adobe PDF(5109Kb)  |  收藏  |  浏览/下载：398/1  |  提交时间：2021/05/14
Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 217
作者:  Ren, Chaowei;  Sun, Ning;  Kong, Ying;  Qu, Xiaojuan;  Liu, Haixia
Adobe PDF(4295Kb)  |  收藏  |  浏览/下载：550/17  |  提交时间：2021/05/28
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190
作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao
Adobe PDF(1964Kb)  |  收藏  |  浏览/下载：327/0  |  提交时间：2020/04/12
Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 304-314
作者:  Zhang, Chengwei;  Han, Xiao-Ran;  Yang, Xiaobao;  Jiang, Biao
Adobe PDF(1870Kb)  |  收藏  |  浏览/下载：853/2  |  提交时间：2018/08/09
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