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Excision of HIV-1 Provirus in Human Primary Cells with Nanocapsuled TALEN Proteins
期刊论文
ACS APPLIED BIO MATERIALS, 2025, 卷号: 8, 期号: 2, 页码: 1227-1239
作者:
Zhao, Ming
;
Wen, Jing
;
Chen, Irvin S. Y.
;
Liu, Jia
;
Lu, Yunfeng
Adobe PDF(6801Kb)
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浏览/下载:66/3
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提交时间:2025/02/28
T-cells
Transcription
Gene editing
Human immunodeficiency virus
Human immunodeficiency virus provirus elimination
Primary T cell
Protein delivery
Response elements
Trans-activation response
Trans-activation response element
Transcription activator-like effector nuclease nanoparticle
Transcription activators
Genome Engineering of Primary and Pluripotent Stem Cell-Derived Hepatocytes for Modeling Liver Tumor Formation
期刊论文
BIOLOGY-BASEL, 2024, 卷号: 13, 期号: 9
作者:
Zhang, Lulu
;
Wang, Xunting
;
Yang, Xuelian
;
Chi, Yijia
;
Chu, Yihang
Adobe PDF(6541Kb)
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浏览/下载:258/1
|
提交时间:2024/10/14
hepatocytes
organoids
human pluripotent stem cells
CRISPR-Cas9
genome editing
Structure and engineering of miniature Acidibacillus sulfuroxidans Cas12f1
期刊论文
NATURE CATALYSIS, 2023, 卷号: 6, 期号: 8, 页码: 695-709
作者:
Wu, Zhaowei
;
Liu, Dongliang
;
Pan, Deng
;
Yu, Haopeng
;
Shi, Jin
Adobe PDF(10884Kb)
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浏览/下载:332/2
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提交时间:2023/08/18
Electron microscopy
Amino-acids
Asymmetric dimers
Cryo-electron microscopy
Dimer formation
Human cells
In-vivo
Motif recognition
Ternary complex
Therapeutic Application
Global Transcriptional and Epigenetic Reconfiguration during Chemical Reprogramming of Human Retinal Pigment Epithelial Cells into Photoreceptor-like Cells
期刊论文
CELLS, 2022, 卷号: 11, 期号: 19
作者:
Deng, Xiaoqian
;
Lee, Ryan
;
Lim, Sin Yee
;
Zhong, Zheng
;
Wang, Jing
Adobe PDF(5492Kb)
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浏览/下载:1241/660
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提交时间:2022/10/27
human retinal pigment epithelial cells
photoreceptor-like cells
chemical reprogramming
single-cell RNA sequencing
DNA methylation sequencing
Alzheimer's Amyloid-beta Accelerates Human Neuronal Cell Senescence Which Could Be Rescued by Sirtuin-1 and Aspirin
期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2022, 卷号: 16
作者:
Li, Yi
Adobe PDF(4523Kb)
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浏览/下载:405/146
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提交时间:2022/12/07
A beta
cell senescence
human neuronal cells
SIRT1
DNA damage
Human platelet lysate (hPL) alters the lineage commitment and paracrine functions of human mesenchymal stem cells via mitochondrial metabolism
期刊论文
APPLIED MATERIALS TODAY, 2022, 卷号: 26
作者:
Du,Ping
;
Tao,Xuelian
;
Liu,Kun
;
Lin,Jiao
;
Shi,Yue
Adobe PDF(6879Kb)
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浏览/下载:404/0
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提交时间:2021/12/17
Biochemistry
Cell engineering
Flowcharting
Mammals
Metabolism
Mitochondria
Platelets
Stem cells
Fetal bovine serum
Human platelet lysate
Lineage commitment
Mesenchymal stem cell
Mitochondrial metabolism
Paracrine
Paracrine function
Platelet lysate
Self renewal
Stem-cell
CRISPR-surfaceome: An online tool for designing highly efficient sgRNAs targeting cell surface proteins
期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, 卷号: 20, 页码: 3833-3838
作者:
Mei, Hong
;
Gu, Qian
;
Wang, Wei
;
Meng, Yu
;
Jiang, Lichun
Adobe PDF(1610Kb)
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浏览/下载:337/7
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提交时间:2022/08/08
Cell membranes
Cytology
Database systems
Proteins
Cell surface proteins
CRISPR
Editing tools
Functional genomics
Genomic studies
Human cells
On-line tools
Online database
Single guide RNA
Surfaceome
Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18, 期号: 1
作者:
Zheng, Dejin
;
Wang, Xiaoyan
;
Zhang, Zhenwu
;
Li, Enqin
;
Yeung, Cheungkwan
Adobe PDF(2853Kb)
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收藏
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浏览/下载:1169/360
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提交时间:2022/01/29
Human embryonic stem cells
mesenchymal stem cells
natural killer cells
innate immunity
immune rejection
Tumor-Specific CircRNA-Derived Antigen Peptide Identification for Hepatobiliary Tumors
期刊论文
ENGINEERING, 2022, 卷号: 22, 页码: 159-170
作者:
Wang, Wenwen
;
Ma, Lili
;
Xing, Zheng
;
Yuan, Tinggan
;
Bao, Jinxia
Adobe PDF(4326Kb)
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收藏
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浏览/下载:326/0
|
提交时间:2022/09/09
Antigens
Interferons
Mass spectrometry
Peptides
T-cells
Tumors
Antigen peptide
Binding peptide
Circular RNA
Hepatobiliary
Human leukocyte antigen
Mass-spectrometry-based immunopeptidomic
Organoids
Patient-derived hepatobiliary tumor organoid
Peptide identification
Tumor antigen
Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+ uniporter
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 卷号: 298, 期号: 1
作者:
Young, Michael P.
;
Schug, Zachary T.
;
Booth, David M.
;
Yule, David, I
;
Mikoshiba, Katsuhiko
Adobe PDF(3650Kb)
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浏览/下载:692/1
|
提交时间:2022/01/21
Amino acids
Calcium
Calcium compounds
Cell signaling
Diseases
Lanthanum compounds
Metabolism
Microcontrollers
Mitochondria
Oxygen
Signaling
ATP level
Biological process
Ca 2+
Calcium signaling
Endoplasmic reticulum
Human cancer cells
Intracellular Ca 2 concentration
Metabolic adaptation
Oxygen consumption
Tricarboxylic acid cycle
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