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The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文
THERANOSTICS, 2022, 卷号: 12, 期号: 17
作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong
Adobe PDF(2552Kb)  |  收藏  |  浏览/下载：713/194  |  提交时间：2022/12/07
Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8
作者:  Luo, Yitian;  Wan, Guoyue;  Zhou, Xuan;  Wang, Qiuwen
Adobe PDF(2839Kb)  |  收藏  |  浏览/下载：644/178  |  提交时间：2021/10/15
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
Adobe PDF(3481Kb)  |  收藏  |  浏览/下载：422/0  |  提交时间：2021/04/01
CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 26, 页码: 12986-12995
作者:  Liu, Fang;  Jiang, Wenyan;  Sui, Yi;  Meng, Wei;  Hou, Linjun
Adobe PDF(2379Kb)  |  收藏  |  浏览/下载：459/7  |  提交时间：2019/08/20
Fsh-Pc-Sce complex mediates active transcription of Cubitus interruptus (Ci) 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2018, 卷号: 10, 期号: 5, 页码: 437-447
作者:  Lv, Xiangdong;  Chen, Hao;  Zhang, Shuo;  Zhang, Zhao;  Pan, Chenyu
Adobe PDF(2103Kb)  |  收藏  |  浏览/下载：1120/360  |  提交时间：2019/01/25
UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing 期刊论文
EMBO REPORTS, 2017, 卷号: 18, 期号: 11, 页码: 1922-1934
作者:  Pan, Chenyu;  Xiong, Yue;  Lv, Xiangdong;  Xia, Yuanxin;  Zhang, Shuo
Adobe PDF(7716Kb)  |  收藏  |  浏览/下载：652/3  |  提交时间：2017/12/12
SUMO regulates somatic cyst stem cell maintenance and directly targets the Hedgehog pathway in adult Drosophila testis 期刊论文
DEVELOPMENT, 2016, 卷号: 143, 期号: 10, 页码: 1655-1662
作者:  Lv, Xiangdong;  Pan, Chenyu;  Zhang, Zhao;  Xia, Yuanxin;  Chen, Hao
Adobe PDF(3408Kb)  |  收藏  |  浏览/下载：1111/392  |  提交时间：2017/07/04
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