消息
×
loading..
×
验证码:
换一张
忘记密码?
记住我
×
统一认证登录
登录
中文版
|
English
上海科技大学知识管理系统
ShanghaiTech University Knowledge Management System
统一认证登录
登录
注册
ALL
ORCID
题名
作者
发表日期
关键词
文献类型
DOI
出处
存缴日期
收录类别
出版者
学习讨论厅
图片搜索
粘贴图片网址
首页
研究单元&专题
作者
文献类型
学科分类
知识图谱
知识整合
学习讨论厅
在结果中检索
研究单元&专题
生命科学与技术学院 [26]
免疫化学研究所 [18]
iHuman研究所 [6]
信息科学与技术学院 [3]
更多...
作者
杨光 [7]
许红涛 [7]
Zonta Fran... [4]
蒋华良 [3]
王明伟 [3]
马培翔 [3]
更多...
文献类型
期刊论文 [33]
会议论文 [2]
专著章节 [1]
发表日期
2024 [5]
2023 [8]
2022 [5]
2021 [4]
2020 [4]
2019 [5]
更多...
出处
ANGEWANDTE... [2]
FRONTIERS ... [2]
FRONTIERS ... [2]
2023 IEEE ... [1]
2024 JOINT... [1]
ACS MEDICI... [1]
更多...
语种
英语 [31]
中文 [1]
资助项目
National N... [3]
Science an... [3]
Fondazione... [2]
Shanghai S... [2]
University... [2]
Chinese Ac... [1]
更多...
资助机构
收录类别
SCI [28]
SCIE [20]
EI [9]
BSCI [1]
CSCD [1]
SCOPUS [1]
更多...
×
知识图谱
KMS
反馈留言
浏览/检索结果:
共36条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
题名升序
题名降序
发表日期升序
发表日期降序
期刊影响因子升序
期刊影响因子降序
WOS被引频次升序
WOS被引频次降序
作者升序
作者降序
An updated patent review of SOS1 inhibitors (2022-present)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024
作者:
Zhou, Guizhen
;
Zhou, Chuan
;
Ma, Xinyi
;
Xu, Jiahang
;
Zhou, Zehui
Adobe PDF(5575Kb)
|
收藏
|
浏览/下载:141/5
|
提交时间:2024/11/11
SOS1
KRAS
cancer
inhibitor
drug discovery
FSO
2
N
3
-Mediated On-DNA Diazo-Transfer Chemistry
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 9
作者:
Huang, Qianping
;
Gu, Yuang
;
Qin, An
;
Ma, Peixiang
;
Xu, Hongtao
Adobe PDF(2300Kb)
|
收藏
|
浏览/下载:280/3
|
提交时间:2024/09/18
DNA-encoded chemical library
diazo-transfer
drug discovery
FSO2N3
Conformational Space Profiling Enhances Generic Molecular Representation for AI-Powered Ligand-Based Drug Discovery
期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 40
作者:
Wang, Lin
;
Wang, Shihang
;
Yang, Hao
;
Li, Shiwei
;
Wang, Xinyu
Adobe PDF(4769Kb)
|
收藏
|
浏览/下载:464/22
|
提交时间:2024/09/08
cellular-level molecular activity modeling
conformational space
drug discovery
ligand-based virtual screening
molecular representation learning
Editorial: Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug development
期刊论文
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15
作者:
Weiss, H. Markus
;
Sugiyama, Yuichi
;
van Duijn, Esther
Adobe PDF(515Kb)
|
收藏
|
浏览/下载:361/1
|
提交时间:2024/08/14
Phase 0
microdosing
drug discovery and development
intra-target microdosing (ITM)
exploratory clinical trials
3R's
modeling and simulations
vulnarable populations
Prompt-based Generation of Natural Language Explanations of Synthetic Lethality for Cancer Drug Discovery
会议论文
2024 JOINT INTERNATIONAL CONFERENCE ON COMPUTATIONAL LINGUISTICS, LANGUAGE RESOURCES AND EVALUATION, LREC-COLING 2024 - MAIN CONFERENCE PROCEEDINGS, Hybrid, Torino, Italy, May 20, 2024 - May 25, 2024
作者:
Zhang, Ke
;
Feng, Yimiao
;
Zheng, Jie
Adobe PDF(1018Kb)
|
收藏
|
浏览/下载:169/1
|
提交时间:2024/07/05
Computational linguistics
Diseases
Domain Knowledge
Natural language processing systems
Anti-cancer therapies
Anticancer drug
Cancer drug
Drug discovery
Explainability
Knowledge graphs
Language model
Natural language explanations
Pre-trained language model
Text-mining
Meta Learning for Low-Data Prediction of Cancer-Specific Synthetic Lethality as Drug Targets
会议论文
2023 IEEE INTERNATIONAL CONFERENCE ON KNOWLEDGE GRAPH (ICKG), Shanghai, China, 1-2 Dec. 2023
作者:
Xin Liu
;
Siyu Tao
;
Jie Zheng
Adobe PDF(539Kb)
|
收藏
|
浏览/下载:190/0
|
提交时间:2024/03/29
Meta-learning
few-sample
synthetic lethality
drug target discovery
Computing the relative binding affinity of ligands based on a pairwise binding comparison network
期刊论文
NATURE COMPUTATIONAL SCIENCE, 2023, 卷号: 3, 期号: 10, 页码: 860-872
作者:
Yu, Jie
;
Li, Zhaojun
;
Chen, Geng
;
Kong, Xiangtai
Adobe PDF(3742Kb)
|
收藏
|
浏览/下载:459/127
|
提交时间:2023/11/10
Binding energy
Computational efficiency
Structural optimization
Web services
Attention mechanisms
Comparison networks
Drug discovery
Fine tuning
Lead optimization
Network-based
Prediction accuracy
Relative binding affinity
Structure-based
Tuning operation
Cynarin alleviates intervertebral disc degeneration via protecting nucleus pulposus cells from ferroptosis
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 165
作者:
Zhang, Pu
;
Rong, Kewei
;
Guo, Jiadong
;
Cui, Lei
;
Kong, Keyu
Adobe PDF(12776Kb)
|
收藏
|
浏览/下载:407/5
|
提交时间:2023/09/08
Cynarin
TNF-& alpha
Intervertebral disc degeneration
Drug discovery
Ferroptosis
Structural biology of SARS-CoV-2 Mpro and drug discovery
期刊论文
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2023, 卷号: 82, 期号: 102667
作者:
Duan, Yinkai
;
Wang, Haofeng
;
Yuan, Zhenghong
;
Yang, Haitao
Adobe PDF(2557Kb)
|
收藏
|
浏览/下载:407/3
|
提交时间:2023/08/13
SARS-CoV-2
Main protease
Structural studies
Autocleavage
Drug discovery
OTTM: an automated classification tool for translational drug discovery from omics data
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2023
作者:
Yang, Xiaobo
;
Zhang, Bei
;
Wang, Siqi
;
Lu, Ye
;
Chen, Kaixian
Adobe PDF(1499Kb)
|
收藏
|
浏览/下载:509/140
|
提交时间:2023/08/28
OTTM
omics data
translational drug discovery
literature mining
hepatocellular carcinoma
首页
上一页
1
2
3
4
下一页
末页