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Recent advances in targeted degradation in the RAS pathway 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2025
作者:  
Adobe PDF(2827Kb)  |  收藏  |  浏览/下载：20/2  |  提交时间：2025/03/25
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文
MOLECULAR DIVERSITY, 2025
作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi
Adobe PDF(4175Kb)  |  收藏  |  浏览/下载：47/1  |  提交时间：2025/03/03
Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282
作者:  Qibang Sui
Adobe PDF(7302Kb)  |  收藏  |  浏览/下载：246/14  |  提交时间：2024/11/27
Prediction of Solvate Based on Graph Attention Network 期刊论文
CRYSTAL GROWTH & DESIGN, 2025, 卷号: 25, 期号: 2
作者:  Sun, Shihui;  Wang, Jian-Rong;  Tang, Lei;  Fan, Zhehuan;  Li, Xutong
Adobe PDF(4799Kb)  |  收藏  |  浏览/下载：53/1  |  提交时间：2025/01/13
Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy 期刊论文
CANCER MEDICINE, 2025, 卷号: 14, 期号: 1
作者:  Wang, Kun;  Zhang, Yingying;  Su, Zhaoming
Adobe PDF(6595Kb)  |  收藏  |  浏览/下载：117/1  |  提交时间：2025/01/20
Prediction of Multi-Pharmacokinetics Property in Multi-Species: Bayesian Neural Network Stacking Model with Uncertainty 期刊论文
MOLECULAR PHARMACEUTICS, 2024, 卷号: 21, 期号: 12
作者:  Zhang, Yuanyuan;  Xie, Zhiyin;  Xiao, Fu;  Yu, Jie;  Fan, Zhehuan
Adobe PDF(5565Kb)  |  收藏  |  浏览/下载：147/1  |  提交时间：2024/11/19
SurfDock is a surface-informed diffusion generative model for reliable and accurate protein-ligand complex prediction 期刊论文
NATURE METHODS, 2024
作者:  Cao, Duanhua;  Chen, Mingan;  Zhang, Runze;  Wang, Zhaokun;  Huang, Manlin
Adobe PDF(4291Kb)  |  收藏  |  浏览/下载：305/70  |  提交时间：2024/06/03
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING 期刊论文
ADVANCED SCIENCE, 2024, 卷号: 12, 期号: 2
作者:  
Adobe PDF(5894Kb)  |  收藏  |  浏览/下载：229/19  |  提交时间：2024/11/27
An updated patent review of SOS1 inhibitors (2022-present) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024
作者:  Zhou, Guizhen;  Zhou, Chuan;  Ma, Xinyi;  Xu, Jiahang;  Zhou, Zehui
Adobe PDF(5575Kb)  |  收藏  |  浏览/下载：126/5  |  提交时间：2024/11/11
Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2024
作者:  Zhang, Yinghui;  Liu, Yadan;  Jiang, Bing;  Chen, Lifan;  Hu, Jie
Adobe PDF(4423Kb)  |  收藏  |  浏览/下载：270/5  |  提交时间：2024/09/08
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