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浏览/检索结果: 共13条,第1-10条 帮助

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IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1
作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei
Adobe PDF(14589Kb)  |  收藏  |  浏览/下载:68/2  |  提交时间:2025/03/03
Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia 期刊论文
CANCER RESEARCH, 2025, 卷号: 85, 期号: 1
作者:  Luo, Ziwei;  Lin, Chencen;  Yu, Chuwei;  Yuan, Changxian;  Wu, Wenyong
Adobe PDF(22554Kb)  |  收藏  |  浏览/下载:156/4  |  提交时间:2025/01/13
Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia 期刊论文
ACTA PHARMACOLOGICA SINICA, 2025
作者:  Chen, Yu-jun;  Zhao, Yu;  Yao, Ming-yue;  Wang, Ya-fang;  Ma, Ming
Adobe PDF(6202Kb)  |  收藏  |  浏览/下载:84/7  |  提交时间:2025/02/12
五环三萜衍生物的医药用途、五环三萜衍生物、包含其的药物组合物 专利
申请号:CN202311207625.0,申请日期: 2024-03-22,类型:发明申请,状态:公开
发明人:  梅良和;  谢成英;  白芳;  王亚芳;  徐岚松
Adobe PDF(8828Kb)  |  收藏  |  浏览/下载:483/1  |  提交时间:2024/03/22
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 41
作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan
Adobe PDF(9804Kb)  |  收藏  |  浏览/下载:332/2  |  提交时间:2024/09/20
Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023
作者:  Yafang Wang;  Mingyue Yao;  Cheng Li (李成);  Kexin Yang;  Xiaolong Qin
Adobe PDF(16153Kb)  |  收藏  |  浏览/下载:363/5  |  提交时间:2024/09/02
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257
作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao
Adobe PDF(11458Kb)  |  收藏  |  浏览/下载:545/8  |  提交时间:2023/07/11
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models 期刊论文
ACTA PHARMACOLOGICA SINICA;, 2023
作者:  Xu, Lan-song;  Zheng, Su-xin;  Mei, Liang-he;  Yang, Ke-xin;  Wang, Ya-fang
Adobe PDF(5479Kb)  |  收藏  |  浏览/下载:321/4  |  提交时间:2023/03/24
Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer 期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8
作者:  Wang, Ya-fang;  Yu, Lei;  Hu, Zong-long;  Fang, Yan-fen;  Shen, Yan-yan
Adobe PDF(5749Kb)  |  收藏  |  浏览/下载:488/176  |  提交时间:2022/09/19
BCL-2 inhibitor synergizes with PI3Kδ inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2022
作者:  Ming-Yue Yao;  Ya-Fang Wang;  Yu Zhao;  Li-Jun Ling;  Ye He
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载:321/1  |  提交时间:2022/11/07
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