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A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11
作者:  Yue, Hangtian;  Xu, Hui;  Ma, Lanping;  Li, Xiyuan;  Yang, Biyu
Adobe PDF(4235Kb)  |  收藏  |  浏览/下载:224/2  |  提交时间:2024/09/21
Anti-inflammatory germacrane-type sesquiterpene lactones from Vernonia sylvatica 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2024, 卷号: 22, 期号: 6
作者:  Wang, Min;  Li, Han;  Hu, Bintao;  Tang, Chunping;  Xu, Hui
Adobe PDF(877Kb)  |  收藏  |  浏览/下载:250/2  |  提交时间:2024/08/26
Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway 期刊论文
RESEARCH, 2023, 卷号: 6
作者:  Jiang, Yu;  Li, Xiyuan;  Qian, Fenghui;  Sun, Bingbing;  Wang, Xiyuan
Adobe PDF(1153Kb)  |  收藏  |  浏览/下载:584/1  |  提交时间:2023/04/21
Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth 期刊论文
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964
作者:  Ding, Chunyong;  Du, Mengyan;  Xiong, Zhi;  Wang, Xue;  Li, Hongji
Adobe PDF(1667Kb)  |  收藏  |  浏览/下载:321/1  |  提交时间:2023/06/02
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1
作者:  Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue
Adobe PDF(5990Kb)  |  收藏  |  浏览/下载:259/86  |  提交时间:2023/01/16
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241
作者:  Shen, Ancheng;  Li, Xiyuan;  Zhang, Yan;  Ma, Jing;  Xiao, Ruoxuan
Adobe PDF(6740Kb)  |  收藏  |  浏览/下载:423/0  |  提交时间:2023/01/16
Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation 期刊论文
CANCER SCIENCE, 2022, 卷号: 113, 期号: 9, 页码: 2974-2985
作者:  Du, Mengyan;  Yu, Ting;  Zhan, Qinjinge;  Li, Han;  Zou, Yiping
Adobe PDF(10387Kb)  |  收藏  |  浏览/下载:304/1  |  提交时间:2022/11/08
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11
作者:  Zhang, Shurui;  Chen, Xiaoxu;  Wu, Chenglin;  Xu, Hui;  Xie, Xiong
Adobe PDF(11423Kb)  |  收藏  |  浏览/下载:519/0  |  提交时间:2022/07/01
Withaphysalins from Medicinal and Edible Physalis minima and Their Anti-inflammatory Activities 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022
作者:  Hu, Bintao;  Li, Han;  Tang, Chunping;  Ke, Chang-Qiang;  Geng, Meiyu
Adobe PDF(2433Kb)  |  收藏  |  浏览/下载:238/0  |  提交时间:2022/05/20
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
Adobe PDF(2015Kb)  |  收藏  |  浏览/下载:538/1  |  提交时间:2021/04/30
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