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Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:  Tao, Hongru;  Wang, Jun;  Lu, Wenchao;  Zhang, Rukang;  Xie, Yiqian
Adobe PDF(975Kb)  |  收藏  |  浏览/下载：689/0  |  提交时间：2019/03/12
Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361
作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan
Adobe PDF(1698Kb)  |  收藏  |  浏览/下载：538/1  |  提交时间：2017/12/12
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
作者:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng
Adobe PDF(4463Kb)  |  收藏  |  浏览/下载：579/1  |  提交时间：2017/12/12
Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay 期刊论文
MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1322-1331
作者:  
Adobe PDF(2878Kb)  |  收藏  |  浏览/下载：417/0  |  提交时间：2017/08/26
Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 9, 页码: 2003-2009
作者:  Sun, Zhongya;  Zhang, Hao;  Chen, Zhifeng;  Xie, Yiqian;  Jiang, Hao
Adobe PDF(1917Kb)  |  收藏  |  浏览/下载：407/0  |  提交时间：2017/07/04
Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 20, 页码: 8166-8181
作者:  Meng, Fanwang;  Cheng, Sufang;  Ding, Hong;  Liu, Shien;  Liu, Yan
Adobe PDF(4696Kb)  |  收藏  |  浏览/下载：584/2  |  提交时间：2017/07/04
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