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NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers 期刊论文
CELL CHEMICAL BIOLOGY, 2024, 卷号: 31, 期号: 6
作者:  Zhu, Xiaotong;  Li, Ye;  Liu, Haixia;  Wang, Yuetong;  Sun, Renhong
Adobe PDF(7503Kb)  |  收藏  |  浏览/下载:448/26  |  提交时间:2024/07/15
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development 期刊论文
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2024, 卷号: 31, 期号: 1
作者:  
Adobe PDF(6453Kb)  |  收藏  |  浏览/下载:756/7  |  提交时间:2023/09/22
Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness 期刊论文
CELL REPORTS, 2023, 卷号: 42, 期号: 10
作者:  Chen, Shengmiao;  Wu, Yiran;  Gao, Yang;  Wu, Chenxu;  Wang, Yuetong
Adobe PDF(5886Kb)  |  收藏  |  浏览/下载:436/14  |  提交时间:2023/11/13
USES OF NAD+ AND//OR NAD+ INHIBITORS AND//OR NAD+ AGONISTS AND COMBINATION PREPARATION THEREOF 专利
申请号:US17616200,申请日期: 2022-12-22,类型:发明申请,状态:实质审查
发明人:  Gaofeng Fan;  Haopeng Wang;  Yuetong Wang;  Fei Wang
Unknown(1175Kb)  |  收藏  |  浏览/下载:300/0  |  提交时间:2022/12/23
Use of NAD+ and//or NAD+ inhibitors and // or NAD+ agonists and combinations thereof 专利
申请号:JP2021572023,申请日期: 2022-08-10,类型:发明申请,状态:授权
发明人:  Fan GF(範高峰);  王こう鵬;  Wang YT(王月桐);  Wang F(王 飛)
Adobe PDF(1031Kb)  |  收藏  |  浏览/下载:250/0  |  提交时间:2022/08/26
FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells 期刊论文
ELIFE, 2022, 卷号: 11
作者:  Zhang, Yanchun;  Xiong, Xuexue;  Zhu, Qi;  Zhang, Jiali;  Chen, Shengmiao
Adobe PDF(2406Kb)  |  收藏  |  浏览/下载:607/5  |  提交时间:2022/05/31
NAD+和//或NAD+抑制剂和//或NAD+激动剂的用途及其联合制剂 专利
申请号:CN201980097190.4,申请日期: 2022-04-05,类型:发明申请,状态:授权
发明人:  范高峰;  王皞鹏
Adobe PDF(1171Kb)  |  收藏  |  浏览/下载:323/0  |  提交时间:2022/04/07
Targeting HSPA1A in ARID2-deficient lung adenocarcinoma 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 10
作者:  Wang, Xue;  Wang, Yuetong;  Fang, Zhaoyuan;  Wang, Hua;  Zhang, Jian
Adobe PDF(6134Kb)  |  收藏  |  浏览/下载:294/0  |  提交时间:2021/12/03
NAD(+) supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells 期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 6
作者:  Wang, Yuetong;  Wang, Fei;  Wang, Lihua;  Qiu, Shizhen;  Yao, Yufeng
Adobe PDF(5745Kb)  |  收藏  |  浏览/下载:514/0  |  提交时间:2021/08/27
Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating βcatenin 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 48, 页码: 18306-18323
作者:  Wang, Yuetong;  Cao, Jian;  Liu, Weiwei;  Zhang, Jiali;  Wang, Zuo
Adobe PDF(5986Kb)  |  收藏  |  浏览/下载:504/13  |  提交时间:2020/01/17
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