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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism 期刊论文
CELL METABOLISM, 2025, 页码: 1-18
作者:  Jie Jiang;  Yuqing Gao;  Jiang Wang;  Yan Huang;  Rong Yang
Adobe PDF(8474Kb)  |  收藏  |  浏览/下载：35/7  |  提交时间：2025/04/05
Rh(III)-catalyzed late-stage C-H alkenylation and macrolactamization for the synthesis of cyclic peptides with unique Trp(C7)-alkene crosslinks 期刊论文
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 8
作者:  Hu, Shulei;  Zhang, Yu;  Xie, Xiong;  Li, Luhan;  Chen, Kaixian
Adobe PDF(2002Kb)  |  收藏  |  浏览/下载：336/1  |  提交时间：2024/10/14
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 页码: 1651-1664
作者:  xiexiong;  Qiaoshuai Lan;  Jinyi Zhao;  Sulin Zhang;  Liu L(刘露)
Adobe PDF(4198Kb)  |  收藏  |  浏览/下载：336/18  |  提交时间：2024/12/02
Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones 期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2023
作者:  Zhang, Shurui;  Hu, Shulei;  Wang, Kean;  Yang, Zhao;  Liu, Hong
Adobe PDF(6743Kb)  |  收藏  |  浏览/下载：423/10  |  提交时间：2023/02/24
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11
作者:  Zhang, Shurui;  Chen, Xiaoxu;  Wu, Chenglin;  Xu, Hui;  Xie, Xiong
Adobe PDF(11423Kb)  |  收藏  |  浏览/下载：518/0  |  提交时间：2022/07/01
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
Adobe PDF(2015Kb)  |  收藏  |  浏览/下载：538/1  |  提交时间：2021/04/30
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-1335
作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian
Adobe PDF(1047Kb)  |  收藏  |  浏览/下载：1507/23  |  提交时间：2020/05/25
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