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Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice
期刊论文
EBIOMEDICINE;, 2023, 卷号: 89
作者:
Peres, Chiara
;
Sellitto, Caterina
;
Nardin, Chiara
;
Putti, Sabrina
;
Orsini, Tiziana
Adobe PDF(5355Kb)
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收藏
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浏览/下载:549/0
|
提交时间:2023/03/24
Adeno-associated viral vectors
Connexin 26
Genodermatosis
In vivo preclinical study
A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 13
作者:
Nardin, Chiara
;
Tettey-Matey, Abraham
;
Donati, Viola
;
Marazziti, Daniela
;
Di Pietro, Chiara
Adobe PDF(3897Kb)
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收藏
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浏览/下载:2597/1736
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提交时间:2022/08/15
connexins
genetically encoded calcium indicators
monoclonal antibodies
drug discovery
genodermatoses
cancer
lentivirus
bicistronic vectors
Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy
期刊论文
BIOMEDICAL OPTICS EXPRESS, 2022, 卷号: 13, 期号: 3, 页码: 1410-1429
作者:
Peres, Chiara
;
Nardin, Chiara
;
Yang, Guang
;
Mammano, Fabio
Adobe PDF(12163Kb)
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收藏
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浏览/下载:452/0
|
提交时间:2022/03/04
Hybrid systems
Photons
Amount of information
Biological samples
Label free
Multimodal microscopy
Nonlinear techniques
Optical architectures
Optical components
Optical process
Optimal performance
Two photon
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 20
作者:
Nardin, Chiara
;
Peres, Chiara
;
Putti, Sabrina
;
Orsini, Tiziana
;
Colussi, Claudia
Adobe PDF(48591Kb)
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收藏
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浏览/下载:1094/472
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提交时间:2021/11/19
photosensitization
nitric oxide
purinergic signaling
calcium signaling
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice
期刊论文
EBIOMEDICINE, 2020, 卷号: 57
作者:
Kuang, Yuanyua
;
Zorzi, Veronica
;
Buratto, Damiano
;
Ziraldo, Gaia
;
Mazzarda, Flavia
Adobe PDF(3596Kb)
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收藏
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浏览/下载:534/5
|
提交时间:2020/08/18
Antibody drug discovery
Genodermatosis
Epidermis
Sebocytes
Calcium
ATP
A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function
期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10
作者:
Ziraldo, Gaia
;
Buratto, Damiano
;
Kuang, Yuanyuan
;
Xu, Liang
;
Carrer, Andrea
Adobe PDF(12985Kb)
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收藏
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浏览/下载:1103/317
|
提交时间:2019/07/01
connexin hemichannels
rare diseases
phage display libraries
therapeutic monoclonal antibodies
molecular dynamics
patch clamp
Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10
作者:
Zorzi, Veronica
;
Paciello, Fabiola
;
Ziraldo, Gaia
;
Peres, Chiara
;
Mazzarda, Flavia
Adobe PDF(5037Kb)
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收藏
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浏览/下载:1380/456
|
提交时间:2017/12/12
cochlea
pannexins
connexins
hair cells
non-sensory cells
auditory brainstem responses
distortion product otoacoustic emissions
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10
作者:
Xu, Liang
;
Carrer, Andrea
;
Zonta, Francesco
;
Qu, Zhihu
;
Ma, Peixiang
Adobe PDF(6237Kb)
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收藏
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浏览/下载:2119/544
|
提交时间:2017/11/14
syndromic autosomal hereditary deafness
cochlea
keratinocytes
connexins
antibody library
antibody structure
epitope identification
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