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Model checking-based decision support system for fault management: A comprehensive framework and application in electric power systems
期刊论文
EXPERT SYSTEMS WITH APPLICATIONS, 2024, 卷号: 247
作者:
Chen, Guangyao
;
He, Peilin
;
Wang, Ziqi
;
Teng, Zixin
;
Jiang, Zhihao
Adobe PDF(2200Kb)
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收藏
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浏览/下载:420/4
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提交时间:2024/02/23
Automata theory
Decision making
Electric power systems
Failure analysis
Intelligent agents
Model checking
Multi agent systems
Fault identifications
Fault management
Inter-agent interactions
Models checking
Partial observability
Reliability and safeties
Rigorous solution
System reliability
System safety
Timed Automata
pyUPPAAL: A Python Package for Risk Analysis of CPS
会议论文
ASSOCIATION FOR COMPUTING MACHINERY, San Antonio, TX, United states, May 9, 2023 - May 12, 2023
作者:
Adobe PDF(918Kb)
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浏览/下载:432/182
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提交时间:2023/11/20
model checking
risk analysis
cyber-physical systems
High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 24
作者:
Lin, Guangyao
Adobe PDF(2352Kb)
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浏览/下载:410/0
|
提交时间:2022/01/10
RXFP3
RXFP4
high-throughput screening
agonist
WNN0109-C011
Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-alpha-cell axis
期刊论文
BIOSCIENCE REPORTS, 2021, 卷号: 41, 期号: 6
作者:
Liu, Qiaofeng
;
Lin, Guangyao
;
Chen, Yan
;
Feng, Wenbo
;
Xu, Yingna
Adobe PDF(3591Kb)
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浏览/下载:630/195
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提交时间:2021/08/16
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
Adobe PDF(4286Kb)
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收藏
|
浏览/下载:242/0
|
提交时间:2021/07/23
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Lin, Guang-yao
;
Lin, Lin
;
Cai, Xiao-qing
;
Dai, An-tao
;
Zhu, Yue
Adobe PDF(2172Kb)
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收藏
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浏览/下载:356/0
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提交时间:2020/04/20
RXFP4
INSL5
high-throughput screening
agonist
JK1
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
Adobe PDF(2565Kb)
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浏览/下载:312/0
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提交时间:2022/12/09
Electron microscopy
Medical imaging
Electron microscopes
Amino acids
Bound structure
Conformational dynamics
Cryo-electron microscopy
Extracellular domains
Extracellular loops
Glucagon-like peptide-1
Metabolic disease
Transmembrane segments
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Full-length human GLP-1 receptor structure without orthosteric ligands
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1
作者:
Wu, Fan
;
Yang, Linlin
;
Hang, Kaini
;
Laursen, Mette
;
Wu, Lijie
Adobe PDF(2812Kb)
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浏览/下载:1039/282
|
提交时间:2020/08/18
W2476 ameliorates beta-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1024-1037
作者:
Li, Ting
;
Lin, Guang-yao
;
Zhong, Li
Adobe PDF(11960Kb)
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收藏
|
浏览/下载:579/0
|
提交时间:2017/08/26
diabetes
glucose
TXNIP
beta-cells
W2476
high-throughput screening
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
作者:
Song, Gaojie
;
Yang, Dehua
;
Wang, Yuxia
;
de Graaf, Chris
;
Zhou, Qingtong
Adobe PDF(5935Kb)
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浏览/下载:1213/7
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提交时间:2017/07/04
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