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Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun
Adobe PDF(1323Kb)  |  收藏  |  浏览/下载：521/7  |  提交时间：2019/05/05
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:  Ye, Xiaoqing;  Zhang, Rukang;  Lian, Fulin;  Zhang, Weiyao;  Lu, Wenchao
Adobe PDF(5234Kb)  |  收藏  |  浏览/下载：451/1  |  提交时间：2019/02/15
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao
Adobe PDF(1688Kb)  |  收藏  |  浏览/下载：504/0  |  提交时间：2018/05/10
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
作者:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng
Adobe PDF(4463Kb)  |  收藏  |  浏览/下载：579/1  |  提交时间：2017/12/12
Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 36, 页码: 8503-8519
作者:  Yue, Liyan;  Du, Juanjuan;  Ye, Fei;  Chen, Zhifeng;  Li, Lianchun
Adobe PDF(2446Kb)  |  收藏  |  浏览/下载：503/0  |  提交时间：2017/07/04
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