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Ultradeep Phosphoproteomics for Assessing Protein Kinase Inhibitor Selectivity on a Proteome Scale
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 5
作者:
Zhang, Yue
;
Han, Ying
;
Li, Xuan
;
Huang, Min
;
Hao, Piliang
Adobe PDF(5285Kb)
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收藏
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浏览/下载:38/1
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提交时间:2025/03/10
Chemoproteomics and Phosphoproteomics Profiling Reveals Salvianolic Acid A as a Covalent Inhibitor of mTORC1
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:
Zheng, Mengmeng
;
Zhang, Yanmei
;
Xu, Yao
;
Han, Ying
;
Wu, Yingli
Adobe PDF(4102Kb)
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收藏
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浏览/下载:329/0
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提交时间:2023/07/11
chemoproteomics
covalentinhibitors
drugtarget identification
phosphoproteomics
salvianolicacid A
Comprehensive Profiling of Rapamycin Interacting Proteins with Multiple Mass Spectrometry-Based Omics Techniques
期刊论文
ANALYTICAL CHEMISTRY, 2023, 卷号: 95, 期号: 22, 页码: 8605-8612
作者:
Xu, Yao
;
Zheng, Mengmeng
;
Gong, Li
;
Liu, Guizhen
;
Qian, Shanshan
Adobe PDF(3754Kb)
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收藏
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浏览/下载:384/0
|
提交时间:2023/06/26
Cell death
Drug interactions
Mass spectrometry
Proteins
'omics'
Adverse side effects
Binding proteins
Chemoproteomics
Drug-protein interactions
Functional interaction
Mechanism of action
Multiple mass
Physical interactions
Rapamycin
Target proteins profiling of irreversible kinase inhibitor pelitinib and discovery of degradation of PRDX4 by label free chemoproteomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 230
作者:
Li, Jing
;
Zheng, Mengmeng
;
Xu, Yao
;
Yang, Xin
;
Kang, Jingwu
Adobe PDF(3465Kb)
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收藏
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浏览/下载:291/0
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提交时间:2023/05/05
Chemoproteomics
Drug target identification
Molecular glue degraders
Pelitinib
Peroxiredoxin 4
Determination of 5-methyldeoxycytosine and oxidized derivatives by nano-liquid chromatography with zwitterionic monolithic capillary column
期刊论文
JOURNAL OF CHROMATOGRAPHY A;, 2023, 卷号: 1693
作者:
Qiu, Danye
;
Liu, Guizhen
;
Li, Feng
;
Kang, Jingwu
Adobe PDF(1658Kb)
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收藏
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浏览/下载:196/0
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提交时间:2023/03/24
DNA hydroxylation
DNA methylation
Nano-liquid chromatography
Zwitterionic monolithic capillary column
Preparation of poly(N-vinylpyrrolidone-co-pentaerythritol triacrylate) monolithic column for hydrophilic interaction chromatography
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2023, 卷号: 46, 期号: 8
作者:
Li, Jing
;
Qiu, Danye
;
Li, Feng
;
Kang, Jingwu
Adobe PDF(2543Kb)
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收藏
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浏览/下载:343/0
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提交时间:2023/03/10
Benzoic acid
Column chromatography
Hydrophilicity
Liquid chromatography
Copolymerisation
Crosslinker
Hydrophilic interaction chromatography
Monolithic capillary column
Monolithic columns
N vinylpyrrolidone
Nano liquid chromatography
Poly-N-vinylpyrrolidone
Polymerization solutions
Situ copolymerization
Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics
期刊论文
ANALYTICAL CHEMISTRY, 2022
作者:
Qian, Shanshan
;
Han, Ying
;
Zhang, Yue
;
Du, Yanan
;
Li, Jing
Adobe PDF(5299Kb)
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收藏
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浏览/下载:369/1
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提交时间:2022/12/16
Profiling protein interactions by purification with capillary monolithic affinity column in combination with label-free quantitative proteomics
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2022, 卷号: 1676
作者:
Liu, Guizhen
;
Du, Yanan
;
Fu, Tao
;
Han, Ying
;
Pan, Lifeng
Adobe PDF(1922Kb)
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收藏
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浏览/下载:365/2
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提交时间:2022/07/15
Affinity chromatography
Chelation
Column chromatography
Fused silica
Molecular biology
Nickel compounds
Purification
Support vector machines
Affinity column
Affinity purification
Capillary monolithic affinity column
Chromatography columns
Immobilized metal affinity chromatography
Label free
Monolithics
Protein-protein interactions
Proteomics
Quantitative proteomics
Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1636, 页码: #VALUE!
作者:
Lou, Chunli
;
Ye, Xiongzhen
;
Chen, Ge
;
Zhu, Jidong
;
Kang, Jingwu
Adobe PDF(964Kb)
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收藏
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浏览/下载:374/1
|
提交时间:2021/04/01
DNA methylation
UHRF1 inhibitor
Capillary electrophoresis
Drug screening
Profiling Drug-Protein Interactions by Micro Column Affinity Purification Combined with Label Free Quantification Proteomics(dagger)
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020
作者:
Gong, Li
;
Xu, Yao
;
Liu, Guizhen
;
Zheng, Mengmeng
;
Zhang, Xuepei
Adobe PDF(1760Kb)
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浏览/下载:354/4
|
提交时间:2020/11/24
Drug
protein interactions
Label
free quantification
Proteomics
Affinity purification
FK506
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